Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Tenepla M treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Tenepla M induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Tenepla M contain metformin, is an oral antidiabetic drug which belongs to the class of biguanide. It is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. Moreover, it also reduces the risk of cardiovascular complications of diabetes.

Dr. R.K Singh MBBS , Diabetology

Yes, Tenepla M can be taken with the statin. There is no serious or harmful interaction have been observed between them. Some studies say that it's possible your blood sugar (blood glucose) level may increase when you take a statin, which may lead to developing type 2 diabetes. The risk is small but important enough that the Food and Drug Administration (FDA) has issued a warning on statin labels regarding blood glucose levels and diabetes.

Dr. Manju Shekhawat MBBS , General Physician

No, you should not take alcohol with Tenepla M, because it can cause serious side effects which includes hypoglycemia (low blood sugar). The risk of hypoglycemia is higher when you're drinking and taking Tenepla M than if you're just taking Tenepla M. Some of the signs of hypoglycemia include dizziness, confusion, and drowsiness.

Dr. Sameer Awadhiya MBBS , Pediatrics

Tenepla M helps in weight loss by reducing appetite and food intake. It also increases the insulin sensitivity in your body to work more effectively. This lead to decreased glucose production increases the use of glucose and decrease the fat deposition further helps in weight loss. However, Tenepla M is not approved for weight loss, this is an off-label use.