Temother is a brand contains Temozolomide, is an oral chemotherapy medication primarily used to treat certain types of brain tumors, including glioblastoma multiforme and anaplastic astrocytoma. It belongs to a class of drugs known as alkylating agents, which work by interfering with the DNA of cancer cells, thereby inhibiting their growth and inducing cell death. Always consult your healthcare provider for personalized medical advice before starting any new medication. 

Uses:

Newly Diagnosed Glioblastoma Multiforme: Temozolomide is administered concomitantly with radiotherapy and subsequently as maintenance treatment.

Refractory Anaplastic Astrocytoma: It is used for adult patients who have experienced disease progression on a drug regimen containing nitrosourea and procarbazine.

Dosage and Administration:

Temozolomide is available in capsule form and is typically taken once daily. The specific dosage and treatment schedule depend on the type and stage of the brain tumor, as well as individual patient factors. For newly diagnosed glioblastoma, the treatment regimen often involves daily dosing during radiotherapy, followed by maintenance cycles. It's crucial to follow your healthcare provider's instructions regarding dosage and duration of treatment.

Common Side Effects:

• Nausea and vomiting

• Loss of appetite

• Hair loss

• Headache

• Fatigue

• Constipation

• Seizures

• Low blood cell counts, leading to increased risk of infection, anemia, or bleeding

Most side effects are manageable and may diminish as your body adjusts to the medication. However, if they persist or become concerning, consult your healthcare provider.

Precautions:

Blood Monitoring: Regular blood tests are necessary to monitor blood cell counts and assess liver function during treatment.

Infection Risk: Due to potential low white blood cell counts, avoid contact with individuals who have infections.

Pregnancy and Breastfeeding: Temozolomide can harm an unborn baby. Women should avoid becoming pregnant while taking this medication and should not breastfeed during treatment.

Vaccinations: Avoid live vaccines during treatment, and consult your healthcare provider before receiving any vaccinations.

Drug Interactions:

Inform your healthcare provider about all medications and supplements you are taking, as temozolomide can interact with other drugs, potentially increasing the risk of side effects or reducing effectiveness.

Storage:

Store temozolomide capsules at room temperature, away from moisture and heat. Keep them out of reach of children and pets.