Dr. Anand Singh MBBS , General Physician

Rifazim works by inhibiting the bacterial protein synthesis which is essential for bacterial growth. The absence of these proteins results in stunned bacterial growth due to which bacteria is not able to survive. For hepatic encephalopathy Rifazim works by inhibiting the growth of enteric ammonia-producing bacteria which are present in our gut, this results in the indirect reduction of serum ammonia level. In irritable bowel syndrome with diarrhea, how Rifazim works are still unknown but it is presumed that it works by changing the bacterial flora in small intestine and reduction in gas.

Dr. Chinmaya Bal MBBS , General Physician

No, Rifazim is not a penicillin. It contains rifaximin which is a broad spectrum antibiotic and an analog of rifampicin. It is a prescription drug that is used in the treatment of travelers’ diarrhea (TD), hepatic encephalopathy, and irritable bowel syndrome with diarrhea (IBS-D).

Dr. Suhas Bhargav MBBS , General Physician

Rifazim in combination with other antibiotics might be used to eradicate Helicobacter pylori (H. pylori) but it is generally not used and not approved for the treatment of the infection caused by H. pylori.

Dr. Chinmaya Bal MBBS , General Physician

Yes, Rifazim is used in the treatment of irritable bowel syndrome with diarrhea (IBS-D). It has been found very effective for IBS-D. Rifazim is given three times a day up to 14 days in patients of irritable bowel syndrome with diarrhea.

Dr. Haleema Yezdani MBBS , General Physician

No, Rifazim does not cause weight gain. It has not been reported by the patients who are taking this drug but Rifazim has been reported to cause weight loss in a few patients with travelers’ diarrhea. If you notice any unusual rapid weight changes after taking this drug then discuss with it your doctor and follow his/her instructions.