Dr. Chinmaya Bal MBBS , General Physician

Yes, RFX is used in the treatment of irritable bowel syndrome with diarrhea (IBS-D). It has been found very effective for IBS-D. RFX is given three times a day up to 14 days in patients of irritable bowel syndrome with diarrhea.

Dr. Anand Singh MBBS , General Physician

RFX works by inhibiting the bacterial protein synthesis which is essential for bacterial growth. The absence of these proteins results in stunned bacterial growth due to which bacteria is not able to survive. For hepatic encephalopathy RFX works by inhibiting the growth of enteric ammonia-producing bacteria which are present in our gut, this results in the indirect reduction of serum ammonia level. In irritable bowel syndrome with diarrhea, how RFX works are still unknown but it is presumed that it works by changing the bacterial flora in small intestine and reduction in gas.

Dr. Saikat Mukherjee MBBS , General Physician

Yes, RFX can be taken with ibuprofen. No drug-drug interaction has been reported between them. It is safe to take RFX along with ibuprofen. 

Dr. Suhas Bhargav MBBS , General Physician

Usually, RFX is given for short-term treatment 2 -14 days which might vary depending on the patient's medical condition. Take RFX as directed by your doctor to ensure complete eradication of infection. Do not take this medicine longer than prescribed duration to avoid bacterial resistance.

Dr. Piyush Malav MBBS, MS , General Surgery

Yes, RFX may cause orange urine because it is an analog of rifampicin. This side effect is reversible and unharmful in nature which goes away after discontinuation of this drug.