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Rafinlar, containing Dabrafenib, is a targeted therapy drug used in the treatment of certain cancers with BRAF V600E or V600K mutations. It is a kinase inhibitor that blocks abnormal cell growth and division, offering a precision medicine approach for patients with these specific mutations.
Uses
Dabrafenib inhibits the activity of mutated BRAF kinase, which is part of the MAPK/ERK signaling pathway. By blocking this pathway, it prevents cancer cells from growing and dividing uncontrollably.
Rafinlar is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Based on research, the following side effects have been observed when Rafinlar is used -
Moderate
Mild
Is the use of Rafinlar safe for pregnant women?
Rafinlar has many dangerous side effects in pregnant women. If you are pregnant, do not consume Rafinlar without medical advice.
Is the use of Rafinlar safe during breastfeeding?
Rafinlar can cause moderate side effects on breastfeeding women. If you feel its side effects, then stop taking this drug and consult your doctor. Take this medicine again only if your doctor advises to do so.
What is the effect of Rafinlar on the Kidneys?
Rafinlar rarely harms the kidneys.
What is the effect of Rafinlar on the Liver?
Side effects of Rafinlar rarely affect the liver.
What is the effect of Rafinlar on the Heart?
Side effects of Rafinlar rarely affect the heart.
Rafinlar should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
If you are suffering from any of the following diseases, you should not take Rafinlar unless your doctor advises you to do so -
Is this Rafinlar habit forming or addictive?
No, you will not get addicted to Rafinlar.
Is it safe to drive or operate heavy machinery when consuming?
You may feel sleepy or tired after taking Rafinlar. So it is best to avoid driving.
Is it safe?
Rafinlar is safe but it is important to consult a doctor before taking it.
Is it able to treat mental disorders?
No, the use of Rafinlar in mental disorders is not effective.
Interaction between Food and Rafinlar
Taking Rafinlar with food does not cause any problems.
Interaction between Alcohol and Rafinlar
Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Rafinlar.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 388-389
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 861
Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Dbl™ dacarbazine (dacarbazine)