Pemgem 500 Injection Information

Pemgem 500 Injection is a prescription medicine that is available as a Injection. Primarily, it is used for the treatment of Non-Small Cell Lung Cancer. Other than this, Pemgem 500 Injection has some other therapeutic uses, which have been discussed ahead.

The optimal dosage of Pemgem 500 Injection is largely dependent on the individual's body weight, medical history, gender and age. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.

Some other side effects of Pemgem 500 Injection have been listed ahead. Such side effects of Pemgem 500 Injection normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.

In addition, Pemgem 500 Injection's effect is Severe during pregnancy and Severe for lactating mothers. Further, the section on Pemgem 500 Injection related warnings talks about Pemgem 500 Injection's effects on the liver, heart and kidney.

The section on Pemgem 500 Injection contraindications lists all such conditions.

Drug reaction of Pemgem 500 Injection with other medicines has been reported. A complete list of these interactions is given below.

In addition to the above precautions for Pemgem 500 Injection, it is important to know that it is not safe while driving, and is not habit-forming.

Pemgem Benefits & Uses
Pemgem Dosage & How to Take
Pemgem Side Effects
Pemgem Related Warnings
Pemgem Contraindications
Frequently asked Questions about Pemgem
Pemgem Interactions with Food and Alcohol

Pemgem 500 Injection Benefits & Uses

Pemgem 500 Injection is used to treat the following -

Other Benefits

Non-Small Cell Lung Cancer
Malignant Mesothelioma

Pemgem 500 Injection Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Head and neck cancer Before or After Meal: As advised by a physician Single Maximum Dose: 830 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: 500 mg/m² IV over 10 minutes on Day 1 of each 21-days cycle, given in combination with cisplatin
Geriatric	Disease: Head and neck cancer Before or After Meal: As advised by a physician Single Maximum Dose: 830 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: 500 mg/m² IV over 10 minutes on Day 1 of each 21-days cycle, given in combination with cisplatin

Pemgem 500 Injection Related Warnings

Is the use of Pemgem 500 Injection safe for pregnant women?

Pemgem shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

Severe
Is the use of Pemgem 500 Injection safe during breastfeeding?

Women who are breastfeeding may experience severe harmful effects after taking Pemgem. It should only be taken after medical advice.

Severe
What is the effect of Pemgem 500 Injection on the Kidneys?

Pemgem may cause harmful effects on kidney. if you feel its having any such effect, then stop taking this drug, and restart only on your doctor's advice.

Moderate
What is the effect of Pemgem 500 Injection on the Liver?

Pemgem is completely safe for the liver.

Safe
What is the effect of Pemgem 500 Injection on the Heart?

You can take Pemgem without any fear of damage to the heart.

Safe

Pemgem 500 Injection Contraindications

If you are suffering from any of the following diseases, you should not take Pemgem 500 Injection unless your doctor advises you to do so -

Kidney Disease
Neutropenia
Pneumonitis
Infertility

Frequently asked Questions about Pemgem 500 Injection

Is this Pemgem 500 Injection habit forming or addictive?

Forming a habit of Pemgem 500 Injection has not been reported.

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should do not do anything that requires concentration and attention as the Pemgem 500 Injection can make you feel drowsy.

Dangerous
Is it safe?

Pemgem 500 Injection should be used only after doctor's advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, Pemgem 500 Injection cannot treat any kind of mental disorder.

No

Pemgem 500 Injection Interactions with Food and Alcohol

Interaction between Food and Pemgem 500 Injection

Taking Pemgem 500 Injection with food is safe.

Safe
Interaction between Alcohol and Pemgem 500 Injection

It is difficult to say anything about the effect of Pemgem 500 Injection and alcohol. No research has been done on this yet.

Unknown

See all substitutes for Pemgem

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 999-1000

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 863

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Alimta (pemetrexed disodium)

Pemgem 500 Injection