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Methofast is a prescription drug, available for use as Injection. It is primarily used for the treatment of Non-Hodgkin Lymphoma, Lymphoma. Secondary and off-label uses of Methofast have also been mentioned below.
The optimal dosage of Methofast is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. For detailed information on this, read through the dosage section.
Methofast also has some side effects, the most common being Abdominal Pain. Besides the aforementioned side effects, there are other adverse effects of Methofast as well, which are listed below. Such side effects of Methofast normally do not last long and go away once the treatment is completed. Consult your doctor if these side effects become worse or stay for a longer duration.
Furthermore, you should know that effect of Methofast is Severe for pregnant women and Severe for women who are breastfeeding. Further, the section on Methofast related warnings talks about Methofast's effects on the liver, heart and kidney.
Individuals suffering from medical conditions like Infections, Liver Disease, Anemia must refrain from the use of Methofast since this can cause severe adverse effects. The section on Methofast contraindications lists all such conditions.
Additionally, Methofast may also adversely react with other medicines. See below for a complete list.
In addition to the above precautions for Methofast, it is important to know that it is safe while driving, and is habit-forming.
Methofast is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
13 - 18 years (Adolescent) |
|
2 - 12 years (Child) |
|
Infant (1 month to 2 years) |
|
Adult(Female) |
|
Is the use of Methofast safe for pregnant women?
Methofast shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.
Is the use of Methofast safe during breastfeeding?
Women who are breastfeeding may experience severe harmful effects after taking Methofast. It should only be taken after medical advice.
What is the effect of Methofast on the Kidneys?
There may be some adverse effects on kidney after taking Methofast. If you observe any such side effects, stop taking this drug. Consume this medicine again only if your doctor advises you to do so.
What is the effect of Methofast on the Liver?
Methofast may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.
What is the effect of Methofast on the Heart?
Very few cases of side effects of Methofast on the heart have been reported.
Methofast should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Methofast unless your doctor advises you to do so -
Is this Methofast habit forming or addictive?
No, you will not get addicted to Methofast.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can comfortably use machinery or drive after taking Methofast since it will not make you feel sleepy.
Is it safe?
Yes, Methofast is safe but you must consult your doctor before taking it.
Is it able to treat mental disorders?
No, the use of Methofast in mental disorders is not effective.
Interaction between Food and Methofast
Due to the absence of research, it is difficult to say how Methofast and food will interact.
Interaction between Alcohol and Methofast
Taking [medicine] and alcohol at the same time may lead to mild side effects. Contact your doctor right away if you observe any side effects.
Methofast is a brand name of methotrexate and it comes in the form of tablet and injection. It is a chemotherapy drug that belongs to the class of drug known as antimetabolites and it also has immunosuppressant properties. It is a prescription drug which is used for the treatment of various types of cancers such as breast cancer, bone cancer, head, and neck cancer. It is also used in the treatment of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis, and Crohn's disease.
No, Methofast is a prescription drug so do not take it without consulting a doctor. It can be harmful for the patient to take this medicine without a doctor's recommendation because it can cause unpleasant side effects. Hence, the patient should seek doctors advice before taking this medication by himself or herself.
No, Methofast does not raise blood pressure (hypertension). It has not been reported by the patients who are taking this drug.
The dosage of this drug may vary depending on the diagnosis and the patient's medical condition. Take Methofast as advised by your doctor. Ideally, oral Methofast has to be taken empty stomach because the presence of food might affect the absorption of this drug from the stomach. Precautions must be taken in patients with bone marrow depression, and improper liver or kidney function.
Yes, Methofast is safe to use, if taken in prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as gingivitis (inflammation of gum), mouth ulcers, and diarrhoea. If you experience above-mentioned side effects after taking this medicine then inform your doctor and follow his/her instructions.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Methotrexate
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 862-863
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 832-834