Metformin + Vildagliptin Tablet - Zavamet 500 Tablet

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    Metformin + Vildagliptin Information

    Metformin + Vildagliptin is a prescription medicine. It is primarily used for the treatment of Diabetes. The alternative uses of Metformin + Vildagliptin have also been explained below.

    The optimal dosage of Metformin + Vildagliptin is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. This information has been provided in detail in the dosage section.

    The most common side effects of Metformin + Vildagliptin are Headache, Diarrhoea, Nausea or vomiting. Apart from the aforementioned side effects, Metformin + Vildagliptin can also lead to other problems, which have been listed below. These side effects of Metformin + Vildagliptin are usually temporary and subside with the completion of treatment. Consult your doctor if these side effects become worse or stay for a longer duration.

    In addition, Metformin + Vildagliptin's effect is Moderate during pregnancy and Safe for lactating mothers. In addition, Metformin + Vildagliptin's effects on the liver, heart and kidney are discussed below in the Metformin + Vildagliptin related warnings section.

    Metformin + Vildagliptin is contraindicated in people with pre-existing medical conditions like Pancreatitis as it can result in adverse effects. Other contraindications of Metformin + Vildagliptin have been discussed in the sections ahead.

    Drug interactions for Metformin + Vildagliptin have been reported in the medical literature. Refer to the list below for further details.

    Along with the above-mentioned precautions, remember that taking Metformin + Vildagliptin is considered not safe while driving, and is not addictive.



    Metformin + Vildagliptin Benefits & Uses

    Metformin + Vildagliptin is used to treat the following -

    Main Benefits

    Other Benefits

    • Diabetes Type 2

    Metformin + Vildagliptin Dosage & How to Take

    This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

    Find the right dosage based on disease and age

    Age Group Dosage
    Adult
    • Disease: Diabetes Type 2
    • Before or After Meal: With meal
    • Single Maximum Dose: 1 Tablet
    • Dosage Form: Tablet
    • Dosage Route: Oral
    • Frequency: 2 daily
    • Course Duration: As directed by the doctor
    • Special Instructions: Dosage strength: Metformin (1000 mg) Vildagliptin (50 mg)/Tablet, or Metformin (850 mg) Vildagliptin (50 mg)/Tablet
    Geriatric
    • Disease: Diabetes Type 2
    • Before or After Meal: With meal
    • Single Maximum Dose: 1 Tablet
    • Dosage Form: Tablet
    • Dosage Route: Oral
    • Frequency: 2 daily
    • Course Duration: As directed by the doctor
    • Special Instructions: Dosage strength: Metformin (1000 mg) Vildagliptin (50 mg)/Tablet, or Metformin (850 mg) Vildagliptin (50 mg)/Tablet


    Metformin + Vildagliptin Side Effects

    Based on research, the following side effects have been observed when Metformin + Vildagliptin is used -

    Severe

    • Dizziness
    • Hypoglycemia (Low blood sugar level)

    Common

    • Headache
    • Diarrhoea
    • Nausea or vomiting
    • Sore throat
    • Nasal congestion

    Metformin + Vildagliptin Related Warnings

    • Is the use of Metformin + Vildagliptin safe for pregnant women?


      Metformin + Vildagliptin can have harmful effects in pregnant women. If you experience any discomfort after using Metformin + Vildagliptin, then discontinue the use and take your doctor's advice.

      Moderate
    • Is the use of Metformin + Vildagliptin safe during breastfeeding?


      Metformin + Vildagliptin does not show any harmful effects in lactating women.

      Safe
    • What is the effect of Metformin + Vildagliptin on the Kidneys?


      Metformin + Vildagliptin can have moderate side effects on the kidney. If you notice any harmful effects, stop taking this drug right away. Consult your doctor before using this medicine again.

      Moderate
    • What is the effect of Metformin + Vildagliptin on the Liver?


      You may experience side effects on your liver after taking Metformin + Vildagliptin. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.

      Moderate
    • What is the effect of Metformin + Vildagliptin on the Heart?


      There is no research available on the side effects of Metformin + Vildagliptin on the heart. Therefore, its impact is unknown.

      Unknown


    Severe Interaction of Metformin + Vildagliptin with Other Drugs

    Metformin + Vildagliptin should not be taken with following medicines due to severe side effects it may cause to patients -

    Severe

    Moderate



    Metformin + Vildagliptin Contraindications

    If you are suffering from any of the following diseases, you should not take Metformin + Vildagliptin unless your doctor advises you to do so -



    Frequently asked Questions about Metformin + Vildagliptin

    • Is this Metformin + Vildagliptin habit forming or addictive?


      Metformin + Vildagliptin is not addictive in nature.

      No
    • Is it safe to drive or operate heavy machinery when consuming?


      After taking Metformin + Vildagliptin, you should not drive or work on any heavy machine, as Metformin + Vildagliptin can make you drowsy.

      Dangerous
    • Is it safe?


      Yes, but take Metformin + Vildagliptin only as per medical advice.

      Safe, but take only on Doctor's advise
    • Is it able to treat mental disorders?


      There is no benefit of taking Metformin + Vildagliptin for mental disorders.

      No

    Metformin + Vildagliptin Interactions with Food and Alcohol

    • Interaction between Food and Metformin + Vildagliptin


      Due to a lack of research, nothing can be said about the consequences of taking Metformin + Vildagliptin together with food.

      Unknown
    • Interaction between Alcohol and Metformin + Vildagliptin


      Information about the interaction of Metformin + Vildagliptin and alcohol is not currently available because this topic has not been researched yet.

      Unknown


    Frequently asked Questions about Metformin + Vildagliptin

    Question over 5 years ago

    Can I take alcohol with Metformin + Vildagliptin?

    Dr. Manju Shekhawat MBBS , General Physician

    No, you should not take alcohol with Metformin + Vildagliptin, because it can cause serious side effects which includes hypoglycemia (low blood sugar). The risk of hypoglycemia is higher when you're drinking and taking Metformin + Vildagliptin than if you're just taking Metformin + Vildagliptin. Some of the signs of hypoglycemia include dizziness, confusion, and drowsiness.

    Question over 5 years ago

    Can I take Metformin + Vildagliptin with gliclazide?

    Dr. Ashish Mishra MBBS , Pathology

    Yes, you can take Metformin + Vildagliptin with gliclazide, no harmful interactions have been reported between them. However, it is not necessary that no interaction can happen between these two. But before taking such kind of combination you must consult your doctor.

    Question over 5 years ago

    Can I take Metformin + Vildagliptin with statin?

    Dr. R.K Singh MBBS , Diabetology

    Yes, Metformin + Vildagliptin can be taken with the statin. There is no serious or harmful interaction have been observed between them. Some studies say that it's possible your blood sugar (blood glucose) level may increase when you take a statin, which may lead to developing type 2 diabetes. The risk is small but important enough that the Food and Drug Administration (FDA) has issued a warning on statin labels regarding blood glucose levels and diabetes.

    Question over 5 years ago

    Does Metformin + Vildagliptin cause sleep problems?

    Dr. Ayush Pandey MBBS, PG Diploma , General Physician

    Yes, Metformin + Vildagliptin can cause some sleep problems, especially insomnia. On the other hand, Metformin + Vildagliptin has proven to be useful for preventing sleep apnea. The exact relationship between Metformin + Vildagliptin and sleep problems is still not clear, and further studies are needed for a clearer understanding.

    Question about 5 years ago

    How does Metformin + Vildagliptin increase lactic acidosis?

    Dr. Manoj Meena MBBS , General Physician

    Lactic acidosis associated with Metformin + Vildagliptin treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Metformin + Vildagliptin induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 



    See all substitutes for Metformin + Vildagliptin


    This medicine data has been created by -

    Vikas Chauhan

    B.Pharma, Pharmacy
    5 Years of Experience


    References

    US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)

    KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276

    April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826

    KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275

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