Mestrolyst 80mg Tablet: Uses, Price, Dosage, Side Effects, Substitute, Buy Online

Mestrolyst 80mg Tablet Information

Mestrolyst contains Megestrol acetate, a synthetic progestational agent primarily used in the treatment of certain cancers and as an appetite stimulant. It plays a significant role in managing weight loss and cachexia in patients with AIDS or cancer.

Uses

Treatment of advanced breast cancer
Treatment of advanced endometrial cancer
Management of anorexia, cachexia, or significant weight loss in patients with AIDS or cancer

Mechanism of Action

Megestrol acetate works by inhibiting the release of gonadotropins from the pituitary gland, resulting in decreased estrogen production, which is beneficial in hormone-sensitive cancers. Additionally, it has appetite-stimulating properties.

Dosage and Administration

Breast Cancer and Endometrial Cancer:

Recommended dose: 40 to 320 mg/day orally, divided into several doses.

Anorexia, Cachexia, or Weight Loss:

Recommended dose: 400 to 800 mg/day orally.
Administration: Take Mestrolyst with or without food as directed by a healthcare provider.

Missed Dose: Take the missed dose as soon as you remember unless it is close to the next scheduled dose.

Overdose: In case of overdose, seek immediate medical attention.

Side Effects

Common side effects:

Weight gain
Increased appetite
Nausea
Weakness
Hypertension
Mood changes

Serious side effects:

Thrombophlebitis
Pulmonary embolism
Adrenal insufficiency

Precautions

Monitor for signs of thromboembolic disorders.
Regularly check blood sugar levels in diabetic patients.
Use cautiously in patients with a history of deep vein thrombosis or pulmonary embolism.

Contraindications

Pregnancy: Mestrolyst is contraindicated in pregnancy due to potential harm to the fetus.
Known hypersensitivity to megestrol acetate or any of its components.

Drug Interactions

Rifampin and other enzyme inducers may reduce the effectiveness of Mestrolyst.
Insulin or oral hypoglycemic agents may require dosage adjustments.

Storage

Store at room temperature between 15°C to 30°C.
Keep out of reach of children.

Mestrolyst Benefits & Uses
Mestrolyst Dosage & How to Take
Mestrolyst Related Warnings
Severe Interaction of Mestrolyst with Other Drugs
Mestrolyst Contraindications
Frequently asked Questions about Mestrolyst
Mestrolyst Interactions with Food and Alcohol

Mestrolyst 80mg Tablet Benefits & Uses

Mestrolyst 80mg Tablet is used to treat the following -

Main Benefits

Anorexia Nervosa

Other Benefits

Mestrolyst 80mg Tablet Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult(Female)	Disease: Breast Cancer Before or After Meal: Either Single Maximum Dose: 160 mg Dosage Form: Tablet Dosage Route: Oral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor
Adult	Disease: Anorexia Nervosa Before or After Meal: Either Single Maximum Dose: 800 mg Dosage Form: Tablet Dosage Route: Oral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor
Geriatric	Disease: Breast Cancer Before or After Meal: Either Single Maximum Dose: 160 mg Dosage Form: Tablet Dosage Route: Oral Frequency: 1 daily Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor

Mestrolyst 80mg Tablet Related Warnings

Is the use of Mestrolyst 80mg Tablet safe for pregnant women?

Mestrolyst can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

Severe
Is the use of Mestrolyst 80mg Tablet safe during breastfeeding?

Women who are breastfeeding, may experience serious side effects after taking Mestrolyst. So it is adviced to consult the doctor before using it.

Severe
What is the effect of Mestrolyst 80mg Tablet on the Kidneys?

Very few cases of side effects of Mestrolyst on kidney have been reported.

Mild
What is the effect of Mestrolyst 80mg Tablet on the Liver?

Very few cases of side effects of Mestrolyst on the liver have been reported.

Mild
What is the effect of Mestrolyst 80mg Tablet on the Heart?

Mestrolyst may have mild side effects on the heart. Most people will never see any effect on the heart.

Mild

Severe Interaction of Mestrolyst 80mg Tablet with Other Drugs

Mestrolyst 80mg Tablet should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Amprenavir

Amprenavir Capsule

Moderate

Acarbose

Phenobarbital

Aprepitant

Emtricitabine,Tenofovir,Efavirenz

Erythromycin

Mestrolyst 80mg Tablet Contraindications

If you are suffering from any of the following diseases, you should not take Mestrolyst 80mg Tablet unless your doctor advises you to do so -

Congestive Heart Failure (CHF)
Migraine
High Blood Pressure
Diabetes
Liver Disease
Kidney Disease

Frequently asked Questions about Mestrolyst 80mg Tablet

Is this Mestrolyst 80mg Tablet habit forming or addictive?

Mestrolyst 80mg Tablet does not cause addiction.

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should do not do anything that requires concentration and attention as the Mestrolyst 80mg Tablet can make you feel drowsy.

Dangerous
Is it safe?

Yes, but consume Mestrolyst 80mg Tablet only on doctor's advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, the use of Mestrolyst 80mg Tablet in mental disorders is not effective.

No

Mestrolyst 80mg Tablet Interactions with Food and Alcohol

Interaction between Food and Mestrolyst 80mg Tablet

Taking Mestrolyst 80mg Tablet with food does not harm your health.

Safe
Interaction between Alcohol and Mestrolyst 80mg Tablet

Due to lack of research, nothing can be said about side effects of consuming alcohol while taking Mestrolyst 80mg Tablet.

Unknown

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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

Mestrolyst 80mg Tablet