Melphalan Benefits & Uses

Melphalan is used to treat the following -

Other Benefits

Melphalan Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Multiple Myeloma Before or After Meal: Either Single Maximum Dose: 2 mg Dosage Form: Tablet Dosage Route: Oral Frequency: 3 daily Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor
Adult(Female)	Disease: Ovarian Cancer Before or After Meal: Either Single Maximum Dose: 200 mcg/kg Dosage Form: Tablet Dosage Route: Oral Frequency: 1 daily Course Duration: 5 days Special Instructions: As prescribed by the doctor
Geriatric	Disease: Multiple Myeloma Before or After Meal: Either Single Maximum Dose: 2 mg Dosage Form: Tablet Dosage Route: Oral Frequency: 3 daily Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor

Melphalan Side Effects

Based on research, the following side effects have been observed when Melphalan is used -

Moderate

Anemia (Read More - Home Remedies for Anaemia)
Reduced blood platelets
Decreased white blood cell count (neutrophils)
Constipation (Read More - Home remedies for constipation)
Peripheral Edema

Mild

Nausea or vomiting
Dyspepsia
Loss of appetite
Dizziness
पेट दर्द

Unknown

Stomatitis (Inflammation of the mouth)
Hair Loss
Diarrhoea
Infection
Abdominal cramp

Melphalan Related Warnings

Is the use of Melphalan safe for pregnant women?

Pregnant women may get severe side effects after taking Melphalan. If you are pregnant, do not take Melphalan without a doctor's advice.

Severe
Is the use of Melphalan safe during breastfeeding?

Melphalan may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

Severe
What is the effect of Melphalan on the Kidneys?

Melphalan has very mild side effects on the kidneys.

Mild
What is the effect of Melphalan on the Liver?

Melphalan has very mild side effects on the liver.

Mild
What is the effect of Melphalan on the Heart?

Melphalan is rarely harmful for the heart.

Mild

Severe Interaction of Melphalan with Other Drugs

Melphalan should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Clozapine

Etanercept

Celecoxib

Naproxen

Naproxen,Esomeprazole

Moderate

Digoxin

Melphalan Contraindications

If you are suffering from any of the following diseases, you should not take Melphalan unless your doctor advises you to do so -

Anemia
Neutropenia
Blood Cancer
Kidney Disease
Liver Disease

Frequently asked Questions about Melphalan

Is this Melphalan habit forming or addictive?

No, you will not get addicted to Melphalan.

No
Is it safe to drive or operate heavy machinery when consuming?

You may feel sleepy or tired after taking Melphalan. So it is best to avoid driving.

Dangerous
Is it safe?

Melphalan should be used only after doctor's advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

There is no benefit of taking Melphalan for mental disorders.

No

Melphalan Interactions with Food and Alcohol

Interaction between Food and Melphalan

Taking Melphalan with food is safe.

Safe
Interaction between Alcohol and Melphalan

No research has been done on this till date. Therefore, it is not known what the effect of taking Melphalan with alcohol will be.

Unknown

See all substitutes for Melphalan

Alkeran Tablet - ₹362
Alkacel 5 Tablet - ₹2751
Alkacel 2 Tablet - ₹2290
Alphalan 2 Tablet - ₹2175
Alphalan 5 Tablet - ₹3725
Melphalan Tablet - ₹2900
Melfalax 2 Tablet - ₹3850
Melfalax 5 Tablet - ₹3850

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Evomela (melphalan)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 861

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 810-812

Melphalan Tablet