Isordil is a prescription drug, available for use as Tablet. It is primarily used for the treatment of Angina. Isordil also has some secondary and off-label uses. These are listed below.
The optimal dosage of Isordil is largely dependent on the individual's body weight, medical history, gender and age. The condition it has been prescribed for, and the route of administration also determine the right dosage. For detailed information on this, read through the dosage section.
Common side effects of Isordil include Peripheral Edema. Besides the aforementioned side effects, there are other adverse effects of Isordil as well, which are listed below. Usually, these side effects of Isordil go away soon, and do not persist beyond the duration of the treatment. If, however, they worsen or do not go away, please speak with your physician.
Furthermore, you should know that effect of Isordil is Severe for pregnant women and Unknown for women who are breastfeeding. It is important to know if Isordil has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Isordil related warnings section.
Isordil can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Isordil in conditions like Low Blood Pressure (Hypotension), Anemia. Other contraindications of Isordil have been discussed in the sections ahead.
Additionally, Isordil may also adversely react with other medicines. A complete list of these interactions is given below.
Along with the above-mentioned precautions, remember that taking Isordil is considered safe while driving, and is addictive.
Isordil is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
Based on research, the following side effects have been observed when Isordil is used -
Moderate
Mild
Common
Is the use of Isordil safe for pregnant women?
Pregnant women may get severe side effects after taking Isordil. If you are pregnant, do not take Isordil without a doctor's advice.
Is the use of Isordil safe during breastfeeding?
Due to lack of research work on this topic, the side effects of Isordil for breastfeeding women are not known.
What is the effect of Isordil on the Kidneys?
There are no side effects of Isordil on the kidneys.
What is the effect of Isordil on the Liver?
There are no any side effects of Isordil on the liver.
What is the effect of Isordil on the Heart?
Side effects of Isordil rarely affect the heart.
Isordil should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Isordil unless your doctor advises you to do so -
Is this Isordil habit forming or addictive?
Forming a habit of Isordil has not been reported.
Is it safe to drive or operate heavy machinery when consuming?
Isordil does not cause dizziness or sleep, so you can drive a vehicle or operate machinery also.
Is it safe?
Yes, but take Isordil only as per medical advice.
Is it able to treat mental disorders?
No, Isordil cannot treat any kind of mental disorder.
Interaction between Food and Isordil
Taking Isordil with food does not cause any problems.
Interaction between Alcohol and Isordil
Consuming Isordil with alcohol can have many serious effects on your body.
Yes, Isordil may cause a headache. It is a common side effect of this drug. However, the exact cause of a headache is unknown. If you experience a severe headache after taking this drug, take a mild painkiller, apply balm and complete rest even after this if the pain does not subside then discuss with your doctor immediately.
Take Isordil 2-3 times a day or as advised by your doctor. It has to be taken on an empty stomach because the presence of food might affect the absorption of this drug from the stomach. Precautions must be taken in patients with glaucoma, hypothyroidism, and improper liver or kidney function.
Isordil contains isosorbide dinitrate which is a vasodilator. It works by causing relaxation of vascular smooth muscle and dilation of the blood vessels (vasodilation) which promotes increase in oxygen and blood supply to the heart this also reduces the workload of the heart (reduces preload and afterload).
Yes, you can take paracetamol and Isordil together. No clinically significant drug interaction has been reported between them. However, if you feel any discomfort after taking this drug along with paracetamol then do not hesitate to inform your doctor.
No, Isordil should not be discontinued without doctors advice even when you start feeling well because discontinuing of this drug on your own might worsen your current medical condition. Hence you are advised to always consult a doctor before discontinuing this medicine.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Isordil® Titradose™ (isosorbide dinitrate)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 543-544
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 653-654