ravi udawat MBBS , General Physician

Glypten M should be taken with food to reduce stomach and bowel side effects, which may experience the first few weeks of treatment. Also, exercise regularly and test for sugar in your blood or urine as directed.

Dr. Ayush Pandey MBBS, PG Diploma , General Physician

Yes, Glypten M can cause some sleep problems, especially insomnia. On the other hand, Glypten M has proven to be useful for preventing sleep apnea. The exact relationship between Glypten M and sleep problems is still not clear, and further studies are needed for a clearer understanding.

Dr. Sameer Awadhiya MBBS , Pediatrics

Glypten M helps in weight loss by reducing appetite and food intake. It also increases the insulin sensitivity in your body to work more effectively. This lead to decreased glucose production increases the use of glucose and decrease the fat deposition further helps in weight loss. However, Glypten M is not approved for weight loss, this is an off-label use.

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Glypten M  treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Glypten M induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Dr. Mayank Yadav MBBS , General Physician

Yes, Glypten M commonly cause stomach upset like diarrhea, abdominal pain, nausea, and vomiting. To avoid these side effects you should take Glypten M with your meal and increase the dose gradually.