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Flucole is a commercial drug that is prescribed in the form of Tablet. Fungal Infections, Candidal Infection, Urinary Tract Infection are some of its major therapeutic uses. Other than this, Flucole has some other therapeutic uses, which have been discussed ahead.
The right dosage of Flucole depends on the age, gender, and medical history of the patient. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.
While these are the most often observed Flucole side effects, there are can be others also. These have been listed below. These side effects of Flucole are usually temporary and subside with the completion of treatment. Consult your doctor if these side effects become worse or stay for a longer duration.
Furthermore, you should know that effect of Flucole is Severe for pregnant women and Safe for women who are breastfeeding. Warnings related to Flucole's effects on the liver, heart and kidney, if any, have been listed below.
Flucole is contraindicated in people with pre-existing medical conditions like Liver Disease as it can result in adverse effects. Some other conditions that can be affected by Flucole are listed in the contraindications section below.
Drug interactions for Flucole have been reported in the medical literature. A complete list of these interactions is given below.
Along with the above-mentioned precautions, remember that taking Flucole is considered not safe while driving, and is not addictive.
Flucole is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| Adult(Female) |
|
| Adult |
|
| Geriatric |
|
| 13 - 18 years (Adolescent) |
|
| 2 - 12 years (Child) |
|
Is the use of Flucole safe for pregnant women?
Flucole should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.
Is the use of Flucole safe during breastfeeding?
Flucole is completely safe for breastfeeding women.
What is the effect of Flucole on the Kidneys?
There may be some adverse effects on kidney after taking Flucole. If you observe any such side effects, stop taking this drug. Consume this medicine again only if your doctor advises you to do so.
What is the effect of Flucole on the Liver?
Flucole has very mild side effects on the liver.
What is the effect of Flucole on the Heart?
Very few cases of side effects of Flucole on the heart have been reported.
Flucole should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
Mild
If you are suffering from any of the following diseases, you should not take Flucole unless your doctor advises you to do so -
Is this Flucole habit forming or addictive?
Forming a habit of Flucole has not been reported.
Is it safe to drive or operate heavy machinery when consuming?
You may feel sleepy or tired after taking Flucole. So it is best to avoid driving.
Is it safe?
Yes, but consume Flucole only on doctor's advice.
Is it able to treat mental disorders?
No, Flucole is not used to treat mental disorders.
Interaction between Food and Flucole
Taking Flucole with food is safe.
Interaction between Alcohol and Flucole
Due to lack of research, there is no information about the side effects of taking Flucole with alcohol.
Rarely, Flucole can cause stomach upset especially when it is intravenously administered (route injectible). On the contrary, oral administration of Flucole has been reported to cause stomach upset such as indigestion, stomach pain, diarrhea, and nausea. Keep your doctor informed in case you are experiencing stomach disturbances while taking this drug.
Flucole inhibit the fungal cytochrome P450 enzyme lanosterol 14- demethylase and thus block ergosterol synthesis leading to membrane abnormalities in the fungus. It kills the fungus by destroying its cell membrane.
No, Usually Flucole does not cause nephrotoxicity. But as per FDA reports patients above 65 years have exhibited acute renal failure hence elderly patients should take Flucole only when prescribed. However, the exact mechanism of renal failure associated with this drug is not yet known.
Rarely, Flucole can cause irregular periods. However, if you're experiencing conditions such as leucorrhoea (whitish or yellowish vaginal discharge), menorrhagia (abnormally heavy bleeding at menstruation) and dysmenorrhea (Painful periods) after taking this medication. Inform your doctor and see a gynaecologist.
Occasionally, Flucole causes constipation when it is taken orally, while the interavenous administration of the medication does not cause constipation or other stomach related issues.
This medicine data has been created by -
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Diflucan® (fluconazole)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 793-794
