Etoxan Information

Etoxan (Etoposide) is a chemotherapy drug that belongs to the class of topoisomerase II inhibitors. It is widely used in the treatment of various cancers by preventing cancer cells from dividing and growing.

Uses

Small cell lung cancer (SCLC).
Testicular cancer.
Lymphomas and certain leukemias.
Ovarian and other solid tumors (off-label in some cases).

Etoposide inhibits the enzyme topoisomerase II, which is critical for DNA replication and repair. By interfering with this process, it induces DNA breaks, leading to apoptosis (programmed cell death) in rapidly dividing cancer cells.

Dosage and Administration

Small Cell Lung Cancer (SCLC): 35–50 mg/m²/day intravenously for 4–5 days or orally.
Testicular Cancer: Typically combined with other agents such as cisplatin or bleomycin.
Dosage adjustments may be necessary for patients with renal or hepatic impairment.

Side Effects

Common: Nausea, vomiting, hair loss, fatigue, low blood cell counts (anemia, leukopenia, thrombocytopenia).
Serious: Severe myelosuppression, infections, hypersensitivity reactions, secondary leukemia.

Precautions

Bone Marrow Suppression: Monitor blood counts regularly.
Infections: Avoid exposure to infections due to immunosuppression.
Pregnancy and Breastfeeding: Not recommended; can harm the fetus or infant.
Drug Interactions: Avoid using with live vaccines and drugs that interact with CYP3A4 enzymes.

Storage
Store at 15–25°C (room temperature) and protect from light. Do not freeze. Keep out of reach of children.

Etoxan Benefits & Uses
Etoxan Dosage & How to Take
Etoxan Side Effects
Etoxan Related Warnings
Severe Interaction of Etoxan with Other Drugs
Etoxan Contraindications
Frequently asked Questions about Etoxan
Etoxan Interactions with Food and Alcohol

Etoxan Benefits & Uses

Etoxan is used to treat the following -

Main Benefits

Small Cell Lung Cancer
Testicular Cancer

Etoxan Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult(Male)	Disease: Testicular Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 166 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor
Geriatric	Disease: Testicular Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 166 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor
Adult	Disease: Small Cell Lung Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 50 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: As directed by the doctor Special Instructions: As prescribed by the doctor

Etoxan Side Effects

Based on research, the following side effects have been observed when Etoxan is used -

Severe

Angioedema
Bronchospasm

Moderate

Anemia (Read More - Home Remedies for Anaemia)
Constipation (Read More - Home remedies for constipation)
Stomatitis (Inflammation of the mouth)
Inflammation of a vein

Mild

Nausea or vomiting
Weakness
पेट दर्द
Hair Loss
Loss of appetite
Chills
Cough
Diarrhoea
Flushing

Etoxan Related Warnings

Is the use of Etoxan safe for pregnant women?

Etoxan has many dangerous side effects in pregnant women. If you are pregnant, do not consume Etoxan without medical advice.

Severe
Is the use of Etoxan safe during breastfeeding?

Etoxan should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

Severe
What is the effect of Etoxan on the Kidneys?

There can be some harmful effects on your kidneys after taking Etoxan. If you witness any side effects, discontinue its use. Consult your medical practitioner, do as he/she suggests.

Moderate
What is the effect of Etoxan on the Liver?

The liver can be affected by Etoxan. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart Etoxan only after medical advice.

Moderate
What is the effect of Etoxan on the Heart?

Etoxan is completely safe for the heart.

Safe

Severe Interaction of Etoxan with Other Drugs

Etoxan should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate

Lovastatin

Bleomycin

Amlodipine,Atorvastatin

Amiodarone

Diltiazem

Etoxan Contraindications

If you are suffering from any of the following diseases, you should not take Etoxan unless your doctor advises you to do so -

Kidney Disease
Liver Disease
Bleeding
Neutropenia

Frequently asked Questions about Etoxan

Is this Etoxan habit forming or addictive?

No, there is no any evidence that Etoxan is addictive.

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should not drive or operate heavy machinery after taking Etoxan as you may feel sleepy.

Dangerous
Is it safe?

Etoxan is safe but it is important to consult a doctor before taking it.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

Etoxan is unable to treat or cure mental disorders.

No

Etoxan Interactions with Food and Alcohol

Interaction between Food and Etoxan

It is safe to take Etoxan with food.

Safe
Interaction between Alcohol and Etoxan

Due to lack of research, there is no information about the side effects of taking Etoxan with alcohol.

Unknown