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Azakem is an antineoplastic agent that works as a hypomethylating agent. It is primarily used in the treatment of certain types of myelodysplastic syndromes (MDS), a group of bone marrow disorders. Azakem helps restore normal gene function, promoting healthy blood cell production and inhibiting the growth of abnormal cells in the bone marrow.
Azakem incorporates into DNA and RNA, inhibiting DNA methyltransferase. This results in hypomethylation of DNA and reactivation of silenced tumor suppressor genes. The drug also disrupts RNA processing, which may contribute to its anti-cancer effects. These mechanisms slow or stop the growth of abnormal cells and promote normal cell development.
Azakem is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| Adult |
|
| Geriatric |
|
Based on research, the following side effects have been observed when Azakem is used -
Severe
Moderate
Mild
Common
Is the use of Azakem safe for pregnant women?
Is the use of Azakem safe during breastfeeding?
What is the effect of Azakem on the Kidneys?
What is the effect of Azakem on the Liver?
What is the effect of Azakem on the Heart?
Azakem should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
If you are suffering from any of the following diseases, you should not take Azakem unless your doctor advises you to do so -
Is this Azakem habit forming or addictive?
Is it safe to drive or operate heavy machinery when consuming?
Is it safe?
Is it able to treat mental disorders?
Interaction between Food and Azakem
Interaction between Alcohol and Azakem
This medicine data has been created by -
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Vidaza (azacitidine)
Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Celazadine® (azacitidine)