Urinary Acidification

Dr. Ayush PandeyMBBS,PG Diploma

January 14, 2019

March 06, 2020

Urinary Acidification
Urinary Acidification

What is urinary acidification?

Acidic urine denotes that the urine has a low pH value. The urine has an acidic pH because of many factors like diet and medications. Increased levels of sodium and excess acid reserved by the body acidifies the urine. The kidneys change the acidic levels in the urine to maintain a constant pH of the blood. If left untreated, high acid levels in the urine can lead to kidney failure.

What are its main associated signs and symptoms?

The main signs and symptoms associated with urinary acidification are:

What are the main causes?

The main causes of urinary acidification are:

  • Cranberry juice
  • Uncontrolled diabetes
  • Respiratory diseases that cause acidosis
  • Dehydration
  • Acidosis (presence of too much acid in the body fluids)
  • Renal tubular acidosis
  • Hyperchloremic acidosis
  • Lactic acidosis
  • Diabetic acidosis
  • Consuming food items like buttermilk, yoghurt and soda
  • Starvation
  • Alcohol overuse
  • Medications, for example, furosemide
  • Diarrhoea
  • Non-vegetarian diet

How is it diagnosed and treated?

Urinary acidification is diagnosed by using the following methods:

  • Acid loading test: This test includes a blood as well as a urine test. It measures the kidney’s function of distributing acid while producing urine in the presence of excess acid in the blood
  • Urine pH test: This test measures the level of acidity in the urine
  • Referring to medical history to look for medications or an underlying disease that can be the cause of urinary acidification
  • An ultrasound of the kidney or bladder may be ordered to look for any abnormalities in these organs

Urinary acidification is treated using the following methods:

  • Balanced vegetarian diet
  • Urinary alkalinising agents
  • Pain relievers
  • Plant-based dietary supplements
  • Drinking plenty of fluids and water
  • Ascorbic acid i.e., vitamin C supplementation.



References

  1. Naim M. Maalouf et al. Metabolic Basis for Low Urine pH in Type 2 Diabetes . Clin J Am Soc Nephrol. 2010 Jul; 5(7): 1277–1281. PMID: 20413437
  2. MedlinePlus Medical Encyclopedia: US National Library of Medicine; Acidosis
  3. Seema Kumar et al. URINARY NET CHARGE IN HYPERCHLOREMIC METABOLIC ACIDOSIS. Indian Pediatrics, VOLUME 35-JANUARY 1998
  4. Patel S, Sharma S. Physiology, Respiratory Acidosis. [Updated 2019 May 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
  5. Siener R, Hesse A. The effect of a vegetarian and different omnivorous diets on urinary risk factors for uric acid stone formation. Eur J Nutr. 2003 Dec;42(6):332-7. PMID: 14673606
  6. Johns Hopkins Medicine [Internet]. The Johns Hopkins University, The Johns Hopkins Hospital, and Johns Hopkins Health System; Urinary Tract Infections
  7. MedlinePlus Medical Encyclopedia: US National Library of Medicine; Acid loading test (pH)
  8. John M Berardi et al. Plant based dietary supplement increases urinary pH . J Int Soc Sports Nutr. 2008; 5: 20. PMID: 18990209
  9. Elisabeth G. E. de Vries et al. Influence of Various Beverages on Urine Acid Output. Cancer Research 46, 430-432, January 1986

Medicines for Urinary Acidification

Medicines listed below are available for Urinary Acidification. Please note that you should not take any medicines without doctor consultation. Taking any medicine without doctor's consultation can cause serious problems.