Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Glipon MF treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Glipon MF induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Dr. Sameer Awadhiya MBBS , Pediatrics

Glipon MF increases the sensitivity of insulin, young women with PCOS often have elevated insulin levels and are more likely to develop diabetes. It is often prescribed for women with PCOS to help prevent diabetes. A lifestyle that includes healthy nutrition and daily exercise is the most important part of a PCOS treatment plan.

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Glipon MF works by decreasing the hepatic glucose production. It also works to lower blood sugar by increasing your sensitivity to insulin and decreasing the amount of glucose that is absorbed from the food you eat.

Dr. Mayank Yadav MBBS , General Physician

Yes, Glipon MF commonly cause stomach upset like diarrhea, abdominal pain, nausea, and vomiting. To avoid these side effects you should take Glipon MF with your meal and increase the dose gradually.

Dr. Ayush Pandey MBBS, PG Diploma , General Physician

Yes, Glipon MF can cause some sleep problems, especially insomnia. On the other hand, Glipon MF has proven to be useful for preventing sleep apnea. The exact relationship between Glipon MF and sleep problems is still not clear, and further studies are needed for a clearer understanding.