Sibofix

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Sibofix Information

Sibofix is a commercial drug that is prescribed in the form of Tablet, Suspension. It is typically used for the treatment of Hepatic Encephalopathy. Other than this, Sibofix has some other therapeutic uses, which have been discussed ahead.

Medical history of the patient along with age and gender determines the dosage of Sibofix. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Detailed information has been provided in the dosage section.

Sibofix also has some side effects, the most common being Flatulence, Bloating or fullness, Constipation. Apart from the aforementioned side effects, Sibofix can also lead to other problems, which have been listed below. Usually, these side effects of Sibofix go away soon, and do not persist beyond the duration of the treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.

Sibofix's effect during pregnancy is Severe and Severe while nursing. Warnings related to Sibofix's effects on the liver, heart and kidney, if any, have been listed below.

Some other conditions that can be affected by Sibofix are listed in the contraindications section below.

Additionally, Sibofix may also adversely react with other medicines. See below for a complete list.

You should also be aware that Sibofix is safe while driving, and is addiction.


Sibofix Benefits & Uses

Sibofix is used to treat the following -

Main Benefits

Other Benefits

Sibofix Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Traveler's Diarrhea
  • Before or After Meal: Either
  • Single Maximum Dose: 200 g
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Traveler's Diarrhea
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Traveler's Diarrhea
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor

Sibofix Side Effects

Based on research, the following side effects have been observed when Sibofix is used -

Moderate

  • Increased Liver Enzymes
  • Peripheral Edema

Mild

Common

Sibofix Related Warnings

  • Is the use of Sibofix safe for pregnant women?


    Sibofix can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

    Severe
  • Is the use of Sibofix safe during breastfeeding?


    Sibofix should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Sibofix on the Kidneys?


    Using Sibofix does not have any harmful effects on kidneys.

    Safe
  • What is the effect of Sibofix on the Liver?


    Sibofix may have mild side effects on the liver. Most people will never see any effect on the liver.

    Mild
  • What is the effect of Sibofix on the Heart?


    There are no any side effects of Sibofix for the heart.

    Safe

Severe Interaction of Sibofix with Other Drugs

Sibofix should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate


Sibofix Contraindications

If you are suffering from any of the following diseases, you should not take Sibofix unless your doctor advises you to do so -


Frequently asked Questions about Sibofix

  • Is this Sibofix habit forming or addictive?


    No, you will not get addicted to Sibofix.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, it is safe to do these activities or work after taking Sibofix as it does not make you drowsy.

    Safe
  • Is it safe?


    Sibofix is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Sibofix is not used to treat mental disorders.

    No

Sibofix Interactions with Food and Alcohol

  • Interaction between Food and Sibofix


    You can take Sibofix with food.

    Safe
  • Interaction between Alcohol and Sibofix


    It is difficult to say anything about the effect of Sibofix and alcohol. No research has been done on this yet.

    Unknown

Frequently asked Questions about Sibofix

Question about 5 years ago

Can I take Sibofix with loperamide?

Dr. MBBS , Pediatrics, Dermatology, General Physician, Dietician, Infectious Disease, Sexual Medicine & Marital Therapy, Obstetrics & Gynaecology, AIDS/HIV Sexually Transmitted Infections

Yes, Sibofix can be taken with loperamide. Loperamide does not appear to interfere with the efficacy of Sibofix. Hence, it is alright to take them together. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.

Question over 5 years ago

Can Sibofix cause orange urine?

Dr. Piyush Malav MBBS, MS , General Surgery

Yes, Sibofix may cause orange urine because it is an analog of rifampicin. This side effect is reversible and unharmful in nature which goes away after discontinuation of this drug.

Question over 5 years ago

Does Sibofix cause weight gain?

Dr. Haleema Yezdani MBBS , General Physician

No, Sibofix does not cause weight gain. It has not been reported by the patients who are taking this drug but Sibofix has been reported to cause weight loss in a few patients with travelers’ diarrhea. If you notice any unusual rapid weight changes after taking this drug then discuss with it your doctor and follow his/her instructions.

Question almost 6 years ago

Does Sibofix cause fatigue?

Dr. MBBS , Pediatrics, Dermatology, General Physician, Dietician, Infectious Disease, Sexual Medicine & Marital Therapy, Obstetrics & Gynaecology, AIDS/HIV Sexually Transmitted Infections

Rarely, Sibofix causes fatigue. It is an uncommon side effect of this drug. However, the exact cause of fatigue is unknown. If you experience tiredness after taking this drug, then try to take some rest even after that if you feel excessive tiredness then do discuss it with your doctor.

Question about 6 years ago

How does Sibofix work?

Dr. Anand Singh MBBS , General Physician

Sibofix works by inhibiting the bacterial protein synthesis which is essential for bacterial growth. The absence of these proteins results in stunned bacterial growth due to which bacteria is not able to survive. For hepatic encephalopathy Sibofix works by inhibiting the growth of enteric ammonia-producing bacteria which are present in our gut, this results in the indirect reduction of serum ammonia level. In irritable bowel syndrome with diarrhea, how Sibofix works are still unknown but it is presumed that it works by changing the bacterial flora in small intestine and reduction in gas.


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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

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