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Neotrexate is a commercial drug that is prescribed in the form of Tablet, Injection. Non-Hodgkin Lymphoma, Lymphoma are some of its major therapeutic uses. Other than this, Neotrexate has some other therapeutic uses, which have been discussed ahead.
The correct dosage of Neotrexate depends on the patient's age, gender, and medical history. The condition it has been prescribed for, and the route of administration also determine the right dosage. For detailed information on this, read through the dosage section.
Neotrexate also has some side effects, the most common being Abdominal Pain. Some other side effects of Neotrexate have been listed ahead. These side effects of Neotrexate are usually temporary and subside with the completion of treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.
Furthermore, you should know that effect of Neotrexate is Severe for pregnant women and Severe for women who are breastfeeding. Further, the section on Neotrexate related warnings talks about Neotrexate's effects on the liver, heart and kidney.
Neotrexate is contraindicated in people with pre-existing medical conditions like Infections, Liver Disease, Anemia as it can result in adverse effects. The section on Neotrexate contraindications lists all such conditions.
Additionally, Neotrexate may also adversely react with other medicines. Refer to the list below for further details.
You should also be aware that Neotrexate is safe while driving, and is addiction.
Neotrexate is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
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Geriatric |
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Is the use of Neotrexate safe for pregnant women?
Pregnant women may get severe side effects after taking Neotrexate. If you are pregnant, do not take Neotrexate without a doctor's advice.
Is the use of Neotrexate safe during breastfeeding?
Neotrexate should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.
What is the effect of Neotrexate on the Kidneys?
Kidney can be affected by Neotrexate. If you experience any unwanted effects of this drug, stop taking it. You should take it again only after medical advice.
What is the effect of Neotrexate on the Liver?
Neotrexate can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.
What is the effect of Neotrexate on the Heart?
Neotrexate is rarely harmful for the heart.
Neotrexate should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Neotrexate unless your doctor advises you to do so -
Is this Neotrexate habit forming or addictive?
No, you will not get addicted to Neotrexate.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can operate a vehicle or heavy machinery after taking Neotrexate since it does not cause drowsiness.
Is it safe?
Yes, Neotrexate is safe but you must consult your doctor before taking it.
Is it able to treat mental disorders?
There is no benefit of taking Neotrexate for mental disorders.
Interaction between Food and Neotrexate
There isn't any research available on the side effects of taking Neotrexate with food.
Interaction between Alcohol and Neotrexate
Drinking alcohol while taking Neotrexate may lead to slight side effects. If you experience any side effects, contact your doctor.
Neotrexate is a brand name of methotrexate and it comes in the form of tablet and injection. It is a chemotherapy drug that belongs to the class of drug known as antimetabolites and it also has immunosuppressant properties. It is a prescription drug which is used for the treatment of various types of cancers such as breast cancer, bone cancer, head, and neck cancer. It is also used in the treatment of autoimmune and inflammatory diseases such as psoriasis, rheumatoid arthritis, and Crohn's disease.
Neotrexate contains methotrexate (a chemotherapy) which is used in the treatment of various types of cancers. Nonetheless, it has been associated with an increased risk for melanoma, non-Hodgkin's lymphoma, and lung cancer.
Yes, Neotrexate is safe to use, if taken in prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as gingivitis (inflammation of gum), mouth ulcers, and diarrhoea. If you experience above-mentioned side effects after taking this medicine then inform your doctor and follow his/her instructions.
No, Neotrexate does not raise blood sugar levels (hyperglycemia). It has not been reported by the patients who are taking it. However, if you are experiencing increased thirst, trouble concentrating, and frequent urination which are symptoms of increased blood sugar levels (hyperglycemia) then do discuss with your doctor.
The dosage of this drug may vary depending on the diagnosis and the patient's medical condition. Take Neotrexate as advised by your doctor. Ideally, oral Neotrexate has to be taken empty stomach because the presence of food might affect the absorption of this drug from the stomach. Precautions must be taken in patients with bone marrow depression, and improper liver or kidney function.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Methotrexate
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 862-863
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 832-834