Tolvaptan Benefits & Uses

Tolvaptan is used to treat the following -

Other Benefits

Heart Failure

Tolvaptan Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Inappropriate Antidiuretic Hormone Secretion (SIADH) Before or After Meal: Either Single Maximum Dose: 15 mg Dosage Form: Tablet Dosage Route: Oral Frequency: 1 daily Course Duration: 1 months Special Instructions: gradually increases upto 60 mg/day
Geriatric	Disease: Inappropriate Antidiuretic Hormone Secretion (SIADH) Before or After Meal: Either Single Maximum Dose: 15 mg Dosage Form: Tablet Dosage Route: Oral Frequency: 1 daily Course Duration: 1 months Special Instructions: gradually increases upto 60 mg/day

Tolvaptan Side Effects

Based on research, the following side effects have been observed when Tolvaptan is used -

Moderate

Loss of appetite

Mild

Headache
Dizziness
Dry Mouth
Fatigue
Diarrhoea
Fever (Read More - Home remedies for fever)
Low energy

Common

Increased thirst
Weakness

Tolvaptan Related Warnings

Is the use of Tolvaptan safe for pregnant women?

Tolvaptan has many dangerous side effects in pregnant women. If you are pregnant, do not consume Tolvaptan without medical advice.

Severe
Is the use of Tolvaptan safe during breastfeeding?

Women who are breastfeeding, may experience serious side effects after taking Tolvaptan. So it is adviced to consult the doctor before using it.

Severe
What is the effect of Tolvaptan on the Kidneys?

Tolvaptan may have mild side effects on the kidneys.

Mild
What is the effect of Tolvaptan on the Liver?

There are no any side effects of Tolvaptan on the liver.

Safe
What is the effect of Tolvaptan on the Heart?

Tolvaptan is completely safe for the heart.

Safe

Severe Interaction of Tolvaptan with Other Drugs

Tolvaptan should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Tolvaptan Contraindications

If you are suffering from any of the following diseases, you should not take Tolvaptan unless your doctor advises you to do so -

Liver Disease
Kidney Disease
Hyperkalemia
Dehydration

Frequently asked Questions about Tolvaptan

Is this Tolvaptan habit forming or addictive?

Tolvaptan does not cause addiction.

No
Is it safe to drive or operate heavy machinery when consuming?

After taking Tolvaptan, you should not drive or work on any heavy machine, as Tolvaptan can make you drowsy.

Dangerous
Is it safe?

Tolvaptan is safe but it is important to consult a doctor before taking it.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, the use of Tolvaptan in mental disorders is not effective.

No

Tolvaptan Interactions with Food and Alcohol

Interaction between Food and Tolvaptan

Some foods when eaten with Tolvaptan can alter the onset of actions. Discuss this with your doctor.

Mild
Interaction between Alcohol and Tolvaptan

Consumption of alcohol and Tolvaptan together may have severe effects on your health.

Severe

See all substitutes for Tolvaptan

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1216-1217

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 525

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Samsca® (tolvaptan)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Jynarque (tolvaptan)

Tolvaptan Tablet