Dr. Ram Saini MD, MBBS , General Physician

Pio M can be taken forever, diabetes is a progressive disease it's possible that more medication and/or insulin may eventually need to be added to the regime. 

Dr. Manju Shekhawat MBBS , General Physician

No, you should not take alcohol with Pio M, because it can cause serious side effects which includes hypoglycemia (low blood sugar). The risk of hypoglycemia is higher when you're drinking and taking Pio M than if you're just taking Pio M. Some of the signs of hypoglycemia include dizziness, confusion, and drowsiness.

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Pio M treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Pio M induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Dr. Vipin Khadse MBBS , General Physician

Pio M is not a known cause of alopecia (hair loss). However, the conditions treated by Pio M type 2 diabetes and PCOS, often list hair loss as a possible symptom.

Dr. Haleema Yezdani MBBS , General Physician

Pio M is used with a proper diet and exercise program, to treat diabetes. It is also used with other medication to reduce the high blood sugar. It is used in a patient with type2 diabetes. It is also used in the treatment of polycystic ovarian syndrome (PCOS) and cancer.