Mibsar Benefits & Uses

Mibsar is used to treat the following -

Main Benefits

Multiple Myeloma

Other Benefits

Mibsar Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Multiple Myeloma Before or After Meal: As advised by a physician Single Maximum Dose: 2 mg Dosage Route: Parenteral Frequency: 2 Weekly Course Duration: 2 weeks Special Instructions: As prescribed by the doctor
Geriatric	Disease: Multiple Myeloma Before or After Meal: As advised by a physician Single Maximum Dose: 2 mg Dosage Route: Parenteral Frequency: 2 Weekly Course Duration: 2 weeks Special Instructions: As prescribed by the doctor

Mibsar Related Warnings

Is the use of Mibsar safe for pregnant women?

Mibsar should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

Severe
Is the use of Mibsar safe during breastfeeding?

Mibsar should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

Severe
What is the effect of Mibsar on the Kidneys?

Using Mibsar does not have any harmful effects on kidneys.

Safe
What is the effect of Mibsar on the Liver?

There may be an adverse effect on the liver after taking Mibsar. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

Moderate
What is the effect of Mibsar on the Heart?

There may be an adverse effect on the heart after taking Mibsar. If you observe any side effects on your body then stop taking this drug. Restart this medicine only if your doctor advises you to do so.

Moderate

Severe Interaction of Mibsar with Other Drugs

Mibsar should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Adalimumab

Phenobarbital

Clozapine

Clonazepam

Infliximab

Moderate

Ergotamine

Carbamazepine

Nitrofurantoin

Mibsar Contraindications

If you are suffering from any of the following diseases, you should not take Mibsar unless your doctor advises you to do so -

Dehydration
Peripheral Neuropathy
Heart Disease
Gastrointestinal Bleeding
Anemia
Liver Disease
Diabetes
Infertility

Frequently asked Questions about Mibsar

Is this Mibsar habit forming or addictive?

Mibsar is not addictive in nature.

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should do not do anything that requires concentration and attention as the Mibsar can make you feel drowsy.

Dangerous
Is it safe?

Mibsar should be used only after doctor's advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, Mibsar cannot treat any kind of mental disorder.

No

Mibsar Interactions with Food and Alcohol

Interaction between Food and Mibsar

When consumed with certain foods, Mibsar may take longer to have an effect. Contact your doctor about this.

Mild
Interaction between Alcohol and Mibsar

Due to lack of research, there is no information about the side effects of taking Mibsar with alcohol.

Unknown

See all substitutes for Mibsar

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 234-235

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 871

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Velcade® (bortezomib)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Bortezomib Aft (Bortezomib)

Mibsar 2mg Injection

Mibsar 2mg Injection

Mibsar Information

Uses

Multiple Myeloma: Mibsar is often used as a first-line treatment in combination with other drugs such as dexamethasone or lenalidomide.

Mantle Cell Lymphoma (MCL): It is approved for the treatment of MCL in patients who have received at least one prior therapy.

Mibsar inhibits the 26S proteasome, a protein complex involved in breaking down unneeded or damaged proteins. By inhibiting the proteasome, Mibsar induces apoptosis (programmed cell death) in cancer cells, disrupting their survival mechanisms.