Xplatin 50 Injection Information

Xplatin 50 Injection is a commercial drug that is prescribed in the form of Injection. It is typically used for the treatment of Colorectal Cancer. Secondary and off-label uses of Xplatin 50 Injection have also been mentioned below.

The right dosage of Xplatin 50 Injection depends on the age, gender, and medical history of the patient. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Detailed information has been provided in the dosage section.

Some other side effects of Xplatin 50 Injection have been listed ahead. These side effects of Xplatin 50 Injection are usually temporary and subside with the completion of treatment. However, if these continue for a longer time, consult your doctor right away.

It is also important to note that Xplatin 50 Injection has a Severe effect for pregnant women and Severe effect on lactating mothers. Further, the section on Xplatin 50 Injection related warnings talks about Xplatin 50 Injection's effects on the liver, heart and kidney.

Xplatin 50 Injection is not recommended if you suffer from certain medical conditions as it can have adverse effects. Arrhythmia are examples of such conditions. Some other conditions that can be affected by Xplatin 50 Injection are listed in the contraindications section below.

Additionally, Xplatin 50 Injection may also adversely react with other medicines. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Xplatin 50 Injection is considered not safe while driving, and is not addictive.

Xplatin Benefits & Uses
Xplatin Dosage & How to Take
Xplatin Side Effects
Xplatin Related Warnings
Severe Interaction of Xplatin with Other Drugs
Xplatin Contraindications
Frequently asked Questions about Xplatin
Xplatin Interactions with Food and Alcohol

Xplatin 50 Injection Benefits & Uses

Xplatin 50 Injection is used to treat the following -

Other Benefits

Colorectal Cancer

Xplatin 50 Injection Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Colorectal Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 140 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: 6 months Special Instructions: Given 85 mg/m2 as IV infusion with combination of 5-fluorouracil/leucovorin in every 2 weeks
Geriatric	Disease: Colorectal Cancer Before or After Meal: As advised by a physician Single Maximum Dose: 140 mg Dosage Route: Parenteral Frequency: doctor administered Course Duration: 6 months Special Instructions: Given 85 mg/m2 as IV infusion with combination of 5-fluorouracil/leucovorin in every 2 weeks

Xplatin 50 Injection Related Warnings

Is the use of Xplatin 50 Injection safe for pregnant women?

Xplatin can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.

Severe
Is the use of Xplatin 50 Injection safe during breastfeeding?

Xplatin should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

Severe
What is the effect of Xplatin 50 Injection on the Kidneys?

Xplatin may have mild side effects on the kidneys.

Mild
What is the effect of Xplatin 50 Injection on the Liver?

Xplatin can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

Moderate
What is the effect of Xplatin 50 Injection on the Heart?

The heart can be affected by Xplatin. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.

Moderate

Severe Interaction of Xplatin 50 Injection with Other Drugs

Xplatin 50 Injection should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Amiodarone

Clozapine

Fentanyl

Etanercept

Haloperidol

Emtricitabine,Tenofovir,Efavirenz

Moderate

Aspirin

Azithromycin

Xplatin 50 Injection Contraindications

If you are suffering from any of the following diseases, you should not take Xplatin 50 Injection unless your doctor advises you to do so -

Heart Disease
Liver Disease
Neutropenia
Peripheral Neuropathy
Arrhythmia

Frequently asked Questions about Xplatin 50 Injection

Is this Xplatin 50 Injection habit forming or addictive?

No, you will not get addicted to Xplatin 50 Injection.

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should do not do anything that requires concentration and attention as the Xplatin 50 Injection can make you feel drowsy.

Dangerous
Is it safe?

Yes, Xplatin 50 Injection is safe but you must consult your doctor before taking it.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

Xplatin 50 Injection is unable to treat or cure mental disorders.

No

Xplatin 50 Injection Interactions with Food and Alcohol

Interaction between Food and Xplatin 50 Injection

You can take Xplatin 50 Injection with food.

Safe
Interaction between Alcohol and Xplatin 50 Injection

Taking alcohol with Xplatin 50 Injection can be dangerous.

Severe

See all substitutes for Xplatin

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 954-956

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 862

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Eloxatin (oxaliplatin)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Oxaliplan™ (oxaliplatin)

Xplatin 50 Injection