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Estradiol is a prescription medicine. It is typically used for the treatment of Post Menopausal Osteoporosis, Urethritis, Vaginal atrophy. Secondary and off-label uses of Estradiol have also been mentioned below.
The correct dosage of Estradiol depends on the patient's age, gender, and medical history. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. This information has been provided in detail in the dosage section.
The most common side effects of Estradiol are Weight gain, Metrorrhagia, Edema. Some other side effects of Estradiol have been listed ahead. Such side effects of Estradiol normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.
It is also important to note that Estradiol has a Severe effect for pregnant women and Severe effect on lactating mothers. In addition, Estradiol's effects on the liver, heart and kidney are discussed below in the Estradiol related warnings section.
Individuals suffering from medical conditions like High Blood Pressure, Blood Clotting Disorders, Thrombophlebitis must refrain from the use of Estradiol since this can cause severe adverse effects. Some other conditions that can be affected by Estradiol are listed in the contraindications section below.
Drug reaction of Estradiol with other medicines has been reported. See below for a complete list.
In addition to the above precautions for Estradiol, it is important to know that it is safe while driving, and is habit-forming.
Estradiol is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult(Male) |
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Geriatric |
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Adult(Female) |
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Is the use of Estradiol safe for pregnant women?
Estradiol can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.
Is the use of Estradiol safe during breastfeeding?
Taking Estradiol may lead to serious side effects if you are breastfeeding. Estradiol should not be taken by breastfeeding women unless prescribed by the doctor.
What is the effect of Estradiol on the Kidneys?
There may be some adverse effects on kidney after taking Estradiol. If you observe any such side effects, stop taking this drug. Consume this medicine again only if your doctor advises you to do so.
What is the effect of Estradiol on the Liver?
Estradiol is rarely harmful for the liver.
What is the effect of Estradiol on the Heart?
You may experience side effects on your heart after taking Estradiol. If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.
Estradiol should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Estradiol unless your doctor advises you to do so -
Is this Estradiol habit forming or addictive?
Estradiol does not cause addiction.
Is it safe to drive or operate heavy machinery when consuming?
Yes, it is safe to do these activities or work after taking Estradiol as it does not make you drowsy.
Is it safe?
Estradiol is safe but it is important to consult a doctor before taking it.
Is it able to treat mental disorders?
No, Estradiol is not used to treat mental disorders.
Interaction between Food and Estradiol
There isn't any research available on the side effects of taking Estradiol with food.
Interaction between Alcohol and Estradiol
Due to lack of research, there is no information about the side effects of taking Estradiol with alcohol.
No, Estradiol is a prescription drug so do not use it without consulting a doctor. It can be harmful for the patient to use this medicine without a doctor's recommendation because it can cause unpleasant side effects. Hence, the patient should seek doctors advice before using this medication by herself.
Yes, Estradiol might cause depression in a few cases only. It is a rare side effect of this drug and the exact cause behind this is unknown.
Yes, Estradiol and progesterone can be taken together because no harmful drug interaction has been reported between them. Hence, it is safe to take Estradiol along with progesterone.
Yes Estradiol can be taken along with levothyroxine at the same time. Levothyroxine does not appear to interfere with the efficacy of Estradiol. Hence, it is alright to take them together. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.
No, Estradiol does not cause acne. It has not been reported by the patients who are taking this drug. In-fact acne might result due to hormonal imbalance (low estradiol levels) caused by menopause and Estradiol is given to correct that hormonal imbalance.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Estrace (estradiol)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 306-309
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 526-528