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Diethylcarbamazine is an allopathic medicine Secondary and off-label uses of Diethylcarbamazine have also been mentioned below. The correct dosage of Diethylcarbamazine depends on the patient's age, gender, and medical history. This information has been provided in detail in the dosage section.
Diethylcarbamazine is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
Based on research, the following side effects have been observed when Diethylcarbamazine is used -
Severe
Mild
Is the use of Diethylcarbamazine safe for pregnant women?
Diethylcarbamazine can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.
Is the use of Diethylcarbamazine safe during breastfeeding?
There is no research available on the side effects of Diethylcarbamazine in breastfeeding women. Therefore, its impact is unknown.
What is the effect of Diethylcarbamazine on the Kidneys?
Diethylcarbamazine may cause harmful effects on kidney. if you feel its having any such effect, then stop taking this drug, and restart only on your doctor's advice.
What is the effect of Diethylcarbamazine on the Liver?
Diethylcarbamazine may have mild side effects on the liver. Most people will never see any effect on the liver.
What is the effect of Diethylcarbamazine on the Heart?
The heart can be affected by Diethylcarbamazine. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.
Diethylcarbamazine should not be taken with following medicines due to severe side effects it may cause to patients -
Moderate
If you are suffering from any of the following diseases, you should not take Diethylcarbamazine unless your doctor advises you to do so -
Is this Diethylcarbamazine habit forming or addictive?
Diethylcarbamazine is not addictive in nature.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can operate a vehicle or heavy machinery after taking Diethylcarbamazine since it does not cause drowsiness.
Is it safe?
Yes, Diethylcarbamazine is safe but you must consult your doctor before taking it.
Is it able to treat mental disorders?
Diethylcarbamazine is unable to treat or cure mental disorders.
Interaction between Food and Diethylcarbamazine
Due to a lack of research, nothing can be said about the consequences of taking Diethylcarbamazine together with food.
Interaction between Alcohol and Diethylcarbamazine
No research has been done on this till date. Therefore, it is not known what the effect of taking Diethylcarbamazine with alcohol will be.
Diethylcarbamazine when used against the microfilariae of o.vulvus in skin and eye can cause permanent damage due to the reactions like uveitis (swelling of the middle layer of the eye), punctuate keratitis (death of cells on the surface of the cornea) and retinal pigment epithelium atrophy (degeneration of retinal pigment epithelium).
Diethylcarbamazine side effects can be minimized by a simultaneous administration of an antihistamine or a corticosteroid. Due to the destruction of a large number of microfilariae, there is a risk of renal and central nervous system complications. This risk can be minimized by withholding the treatment with an anthelmintic drug, removal of microfilariae before the administration of Diethylcarbamazine and administering a single dose of ivermectin.
Animal studies have demonstrated a few heart-related adverse effects of Diethylcarbamazine, however, there is a dearth of data in human beings. Thus, it is not yet clear if Diethylcarbamazine has any adverse effects on the heart. However, if you experience unusual signs related to the heart with the intake of Diethylcarbamazine, please call your doctor immediately.
No, Diethylcarbamazine is not used for the treatment of ocular onchocerciasis because of the fear of antigen-antibody inflammatory reaction. Ivermectin is now used of the treatment of ocular onchocerciasis. Onchocerciasis is also known African River Blindness. It is caused by O. volvulus and it can lead to severe visual impairment.
No, you must not discontinue Diethylcarbamazine on your own as it might lead to a replase if the infection if it is not treated completely. It is recommended that you speak to your doctor before discontinuing Diethylcarbamazine.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 853