Decitamyl Information

Decitamyl (Decitabine) is a chemotherapy drug belonging to the class of hypomethylating agents. It is primarily used for treating myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML). Decitabine works by inhibiting DNA methylation, which can reactivate genes responsible for normal cell growth and differentiation.

Uses

Myelodysplastic Syndromes (MDS):

Used in the treatment of patients with MDS, including refractory anemia, chronic myelomonocytic leukemia (CMML), and other related conditions.

Acute Myeloid Leukemia (AML):

Effective in treating newly diagnosed AML, especially in older patients who are not candidates for intensive chemotherapy.

Decitabine incorporates into the DNA during replication and inhibits DNA methyltransferases. This leads to hypomethylation of DNA, allowing re-expression of tumor-suppressor genes and inhibiting the proliferation of cancer cells.

Decitamyl Benefits & Uses
Decitamyl Dosage & How to Take
Decitamyl Side Effects
Decitamyl Related Warnings
Severe Interaction of Decitamyl with Other Drugs
Decitamyl Contraindications
Frequently asked Questions about Decitamyl
Decitamyl Interactions with Food and Alcohol

Decitamyl Benefits & Uses

Decitamyl is used to treat the following -

Main Benefits

Myelodysplastic Syndrome

Decitamyl Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Myelodysplastic Syndrome Before or After Meal: As advised by a physician Single Maximum Dose: 50 mg Dosage Route: Parenteral Frequency: 1 daily Course Duration: 5 days Special Instructions: Given as a continuous intravenous infusion over 1 hour

Decitamyl Side Effects

Based on research, the following side effects have been observed when Decitamyl is used -

Moderate

Decreased white blood cell count (neutrophils)
Anemia (Read More - Home Remedies for Anaemia)
Reduced blood platelets
Edema
Erythema
Confusion

Mild

Nausea or vomiting
Headache
Fever (Read More - Home remedies for fever)
Infection
Nosebleed (Read More - How to stop a nosebleed)
Diarrhoea

Common

Pneumonitis

Decitamyl Related Warnings

Is the use of Decitamyl safe for pregnant women?

Decitamyl shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

Severe
Is the use of Decitamyl safe during breastfeeding?

In the absence of any scientific study about the side effects of Decitamyl in breastfeeding women, information on safety of Decitamyl is unavailable.

Unknown
What is the effect of Decitamyl on the Kidneys?

There may be some adverse effects on kidney after taking Decitamyl. If you observe any such side effects, stop taking this drug. Consume this medicine again only if your doctor advises you to do so.

Moderate
What is the effect of Decitamyl on the Liver?

You may experience side effects on your liver after taking Decitamyl. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.

Moderate
What is the effect of Decitamyl on the Heart?

Side effects of Decitamyl rarely affect the heart.

Mild

Severe Interaction of Decitamyl with Other Drugs

Decitamyl should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Celecoxib

Clozapine

Diclofenac

Moderate

Warfarin

Azathioprine

Apixaban

Decitamyl Contraindications

If you are suffering from any of the following diseases, you should not take Decitamyl unless your doctor advises you to do so -

Anemia
Fungal Infections
Kidney Disease
Liver Disease
Allergy

Frequently asked Questions about Decitamyl

Is this Decitamyl habit forming or addictive?

Forming a habit of Decitamyl has not been reported.

No
Is it safe to drive or operate heavy machinery when consuming?

Yes, you can comfortably use machinery or drive after taking Decitamyl since it will not make you feel sleepy.

Safe
Is it safe?

Yes, but take Decitamyl only as per medical advice.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

No, Decitamyl cannot treat any kind of mental disorder.

No

Decitamyl Interactions with Food and Alcohol

Interaction between Food and Decitamyl

There is no information on the effects of taking Decitamyl with food, because this topic has not been scientifically researched yet.

Unknown
Interaction between Alcohol and Decitamyl

Due to lack of research, there is no information about the side effects of taking Decitamyl with alcohol.

Unknown

See all substitutes for Decitamyl

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Dacogen® (decitabine)

Decitamyl 50mg Injection