Tegura capsule is a prescription medication used in the treatment of colorectal cancer. It combines two active ingredients: Tegafur (100mg) and Uracil (224mg). Tegafur is a prodrug that converts into 5-fluorouracil (5-FU) in the body, interfering with the growth of cancer cells. Uracil enhances the effectiveness of Tegafur by inhibiting the breakdown of 5-FU, allowing it to remain active longer. Always consult your healthcare provider before starting any new medication. Inform them of your complete medical history and any other medications you are taking to ensure the safe and effective use.

Uses:

• Treatment of cancer of the colon and rectum.

Dosage and Administration:

• The typical regimen involves taking for 28 consecutive days, followed by a 7-day break. This 35-day cycle is then repeated. It's essential to follow your doctor's instructions regarding dosage and duration.

Common Side Effects:

• Nausea
• Vomiting
• Tiredness
• Mouth sores
• Sore tongue
• Stomach pain
• Diarrhea
• Loss of appetite
• Decreased blood cell counts (red cells, white cells, and platelets)

Most side effects are manageable and may diminish as your body adjusts to the medication. However, if they persist or become concerning, consult your doctor. 

Safety Advice:

• Alcohol: The interaction with alcohol is not well-documented. It's advisable to consult your doctor before consuming alcohol during treatment.
• Pregnancy: It is highly unsafe during pregnancy due to potential harm to the developing baby. Women of childbearing age should use effective contraception during treatment.
• Breastfeeding: Information during breastfeeding is limited. Consult your doctor before breastfeeding while on this medication.
• Driving: It may cause side effects such as tiredness, nausea, or blurred vision, which could affect your ability to drive. Exercise caution when driving or operating machinery.
• Kidney and Liver: Limited information is available regarding patients with kidney or liver disease. Discuss your medical history with your doctor to determine if it is suitable for you.

Precautions:

• Avoid using antacids within 2 hours of taking.
• Stay hydrated by drinking plenty of water during treatment.
• To reduce the risk of infection, avoid crowds or contact with individuals who have colds. Report any signs of infection, such as fever, to your doctor promptly.
• To prevent mouth sores, use a soft toothbrush and rinse your mouth with saline water at least three times a day.
• To manage nausea, take anti-nausea medications as prescribed and eat small, frequent meals.
• Consume foods that may help reduce diarrhea and ensure adequate rest.