Silymarin + Ursodiol (Ursodeoxycholic Acid): Uses, Price, Dosage, Side Effects, Substitute, Buy Online

Silymarin + Ursodiol (Ursodeoxycholic Acid) Benefits & Uses

Silymarin + Ursodiol (Ursodeoxycholic Acid) is used to treat the following -

Other Benefits

Non-Alcoholic Fatty Liver Disease
Liver Disease

Silymarin + Ursodiol (Ursodeoxycholic Acid) Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
Adult	Disease: Non-Alcoholic Fatty Liver Disease Before or After Meal: Either Single Maximum Dose: 1 Tablet Dosage Form: Tablet Dosage Route: Oral Frequency: 3 daily Course Duration: As directed by the doctor Special Instructions: strength 300 mg ursodiol and 140 mg silymarin
Geriatric	Disease: Non-Alcoholic Fatty Liver Disease Before or After Meal: Either Single Maximum Dose: 1 Tablet Dosage Form: Tablet Dosage Route: Oral Frequency: 3 daily Course Duration: As directed by the doctor Special Instructions: strength 300 mg ursodiol and 140 mg silymarin

Silymarin + Ursodiol (Ursodeoxycholic Acid) Side Effects

Based on research, the following side effects have been observed when Silymarin + Ursodiol (Ursodeoxycholic Acid) is used -

Common

Diarrhoea
Nausea or vomiting

Silymarin + Ursodiol (Ursodeoxycholic Acid) Related Warnings

Is the use of Silymarin + Ursodiol (Ursodeoxycholic Acid) safe for pregnant women?

Silymarin + Ursodiol (Ursodeoxycholic Acid) may cause moderate side effects during pregnancy. If you feel its harmful effects, then stop taking this drug immediately, and do not take Silymarin + Ursodiol (Ursodeoxycholic Acid) again without your doctor's advice.

Moderate
Is the use of Silymarin + Ursodiol (Ursodeoxycholic Acid) safe during breastfeeding?

Silymarin + Ursodiol (Ursodeoxycholic Acid) may cause serious side effects in breastfeeding women, so do not take this drug without doctor's advice.

Severe
What is the effect of Silymarin + Ursodiol (Ursodeoxycholic Acid) on the Kidneys?

There may be some severe side effects of Silymarin + Ursodiol (Ursodeoxycholic Acid) on your kidney. Do not take it unless a doctor says so.

Severe
What is the effect of Silymarin + Ursodiol (Ursodeoxycholic Acid) on the Liver?

There are no any side effects of Silymarin + Ursodiol (Ursodeoxycholic Acid) on the liver.

Safe
What is the effect of Silymarin + Ursodiol (Ursodeoxycholic Acid) on the Heart?

The heart can be affected by Silymarin + Ursodiol (Ursodeoxycholic Acid). If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.

Moderate

Severe Interaction of Silymarin + Ursodiol (Ursodeoxycholic Acid) with Other Drugs

Silymarin + Ursodiol (Ursodeoxycholic Acid) should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Fenofibrate

Moderate

Losartan

Phenytoin

Aluminium hydroxide

Ciprofloxacin

Colestipol

Colestipol Tablet

Silymarin + Ursodiol (Ursodeoxycholic Acid) Contraindications

If you are suffering from any of the following diseases, you should not take Silymarin + Ursodiol (Ursodeoxycholic Acid) unless your doctor advises you to do so -

Drug Allergy
Diabetes
Hepatic Encephalopathy
Jaundice
Liver Disease
Jaundice
Pancreatitis

Frequently asked Questions about Silymarin + Ursodiol (Ursodeoxycholic Acid)

Is this Silymarin + Ursodiol (Ursodeoxycholic Acid) habit forming or addictive?

Silymarin + Ursodiol (Ursodeoxycholic Acid) does not cause addiction.

No
Is it safe to drive or operate heavy machinery when consuming?

No, you should not drive or operate heavy machinery after taking Silymarin + Ursodiol (Ursodeoxycholic Acid) as you may feel sleepy.

Dangerous
Is it safe?

Yes, Silymarin + Ursodiol (Ursodeoxycholic Acid) is safe but you must consult your doctor before taking it.

Safe, but take only on Doctor's advise
Is it able to treat mental disorders?

Silymarin + Ursodiol (Ursodeoxycholic Acid) is unable to treat or cure mental disorders.

No

Silymarin + Ursodiol (Ursodeoxycholic Acid) Interactions with Food and Alcohol

Interaction between Food and Silymarin + Ursodiol (Ursodeoxycholic Acid)

Due to the absence of research, it is difficult to say how Silymarin + Ursodiol (Ursodeoxycholic Acid) and food will interact.

Unknown
Interaction between Alcohol and Silymarin + Ursodiol (Ursodeoxycholic Acid)

Due to lack of research, there is no information about the side effects of taking Silymarin + Ursodiol (Ursodeoxycholic Acid) with alcohol.

Unknown

Frequently asked Questions about Silymarin + Ursodiol (Ursodeoxycholic Acid)

Question over 5 years ago

Can Silymarin + Ursodiol (Ursodeoxycholic Acid) cure fatty liver?

Dr. Amit Singh MBBS , General Physician

Silymarin + Ursodiol (Ursodeoxycholic Acid) is used in the treatment of fatty liver in combination with other drugs. It helps in improving liver functions with assists in speedy recovery.

Question almost 6 years ago

How does Silymarin + Ursodiol (Ursodeoxycholic Acid) work?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

Silymarin + Ursodiol (Ursodeoxycholic Acid) contains silymarin which is a polyphenolic flavonoid obtained from plant milk thistle (Silybum marianum). It is presumed that Silymarin + Ursodiol (Ursodeoxycholic Acid) works through multiple mechanisms. It prevents the formation of reactive oxygen species (free radicals) that damages the liver which affects its normal functioning. It also reduces the inflammation and stimulates the liver cells to produce proteins.

Question over 5 years ago

Can Silymarin + Ursodiol (Ursodeoxycholic Acid) lower SGPT?

Dr. Anand Singh MBBS , General Physician

Yes, Silymarin + Ursodiol (Ursodeoxycholic Acid) lowers the SGPT (serum glutamic pyruvic transaminase or alanine transaminase) levels in the blood. This occurs due to the hepatoprotective (liver protective) action of this drug which helps in preventing the liver damage that lowers the SGPT levels in our blood.

Question over 5 years ago

Does Silymarin + Ursodiol (Ursodeoxycholic Acid) lower cholesterol?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

Yes, Silymarin + Ursodiol (Ursodeoxycholic Acid) lowers cholesterol levels in the blood because it inhibits the synthesis of bad cholesterol (LDL and VLDL) and it also increases the levels of good cholesterol (HDL) in our body.

Question almost 6 years ago

Can I discontinue Silymarin + Ursodiol (Ursodeoxycholic Acid) on my own without doctors advice?

Dr. Suhas Bhargav MBBS , General Physician

No, Silymarin + Ursodiol (Ursodeoxycholic Acid) should not be discontinued without doctors advice. You are recommended to always consult a doctor before discontinuing this medicine.

See all substitutes for Silymarin + Ursodiol (Ursodeoxycholic Acid)

Ulyses Plus Tablet - ₹299
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Ursodox Plus Tablet - ₹326
Udimarin Tablet - ₹382
Actimarin Tablet - ₹200
Actimarin Forte Tablet - ₹350
Gemiuro Plus Tablet - ₹350
Udimarin Forte Tablet - ₹365
Udiplus Tablet - ₹351
Udibon Tablet - ₹430
Ursetor Plus Tablet - ₹306
Ursokem Plus Tablet - ₹375
Silymarin + Ursodiol (Ursodeoxycholic Acid) Tablet - ₹306

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1344-1345

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 671

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Urso 250® / Urso Forte® (ursodiol)

Highlights of Prescribing Information [Internet]: URSO 250® / URSO Forte® (ursodiol) TABLETS . Initial U.S. Approval: 1997

Gholamreza Karimi,1,* Maryam Vahabzadeh,2 Parisa Lari,2 Marziyeh Rashedinia,2 and Mohammad Moshiri2 [Internet]: “Silymarin”, a Promising Pharmacological Agent for Treatment of Diseases. PMCID: PMC3586829 PMID: 23492971