Dr. Manju Shekhawat MBBS , General Physician

No, you should not take alcohol with Ronymet, because it can cause serious side effects which includes hypoglycemia (low blood sugar). The risk of hypoglycemia is higher when you're drinking and taking Ronymet than if you're just taking Ronymet. Some of the signs of hypoglycemia include dizziness, confusion, and drowsiness.

Dr. Sameer Awadhiya MBBS , Pediatrics

Yes, you can take Ronymet with a beta-blocker. People with diabetes tend to develop heart disease or stroke at an earlier age than the general population. One reason for this is that high glucose levels increase your risk of high blood pressure (hypertension). No harmful interactions are seen between them. However, a recent study suggests that beta-blockers can decrease the plasma level of Ronymet and long-term use can increase lactic acid and uric acid in the blood.

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Ronymet treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Ronymet induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Dr. Ashish Mishra MBBS , Pathology

Yes, you can take Ronymet with gliclazide, no harmful interactions have been reported between them. However, it is not necessary that no interaction can happen between these two. But before taking such kind of combination you must consult your doctor.

Dr. Sameer Awadhiya MBBS , Pediatrics

Ronymet helps in weight loss by reducing appetite and food intake. It also increases the insulin sensitivity in your body to work more effectively. This lead to decreased glucose production increases the use of glucose and decrease the fat deposition further helps in weight loss. However, Ronymet is not approved for weight loss, this is an off-label use.