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Oplatin Injection contains Oxaliplatin, a platinum-based chemotherapy drug used to treat colon and rectal cancers. It works by inhibiting the growth of cancer cells.
Uses:
Oxaliplatin is a platinum-based chemotherapy drug that exerts its anticancer effects by interfering with the DNA of cancer cells. The mechanism of action involves the following steps:
DNA Intercalation and Crosslinking: Oxaliplatin is taken up by the cancer cell and undergoes conversion into its active form. It binds to the DNA in the cell, creating both intra- and inter-strand crosslinks in the DNA structure.
Inhibition of DNA Replication and Transcription: These crosslinks prevent the DNA from unwinding and replicating properly, which interferes with the cell's ability to replicate its genetic material and divide. This leads to the inhibition of DNA replication and transcription.
Induction of Apoptosis: The DNA damage caused by oxaliplatin triggers cellular mechanisms that induce programmed cell death (apoptosis). This process ultimately kills the cancer cell and helps to control tumor growth.
Platinum-DNA Adduct Formation: Oxaliplatin forms platinum-DNA adducts, which are highly cytotoxic. These adducts further prevent proper cell division and cause cell cycle arrest at various checkpoints.
Oxaliplatin is particularly effective in treating colorectal cancer due to its ability to damage cancerous cells, leading to their death and preventing tumor progression.
Dosage and Administration:
Oplatin Injection is administered intravenously by a qualified healthcare professional. The dosage and frequency are determined by the treating physician based on the patient's condition. It is crucial to follow the doctor's instructions precisely to avoid serious side effects.
Common Side Effects:
Most side effects do not require medical attention and may subside as the body adjusts to the medication. However, consult your doctor if they persist or cause concern.
Warnings and Precautions:
Storage:
Store in a refrigerator (2°C – 8°C). Do not freeze. Keep the vial in the outer carton to protect from light.
Oplatin 50mg Injection is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
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Geriatric |
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Based on research, the following side effects have been observed when Oplatin 50mg Injection is used -
Severe
Moderate
Mild
Is the use of Oplatin 50mg Injection safe for pregnant women?
Oplatin has many dangerous side effects in pregnant women. If you are pregnant, do not consume Oplatin without medical advice.
Is the use of Oplatin 50mg Injection safe during breastfeeding?
Women who are breastfeeding may experience severe harmful effects after taking Oplatin. It should only be taken after medical advice.
What is the effect of Oplatin 50mg Injection on the Kidneys?
Oplatin rarely harms the kidneys.
What is the effect of Oplatin 50mg Injection on the Liver?
Oplatin may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.
What is the effect of Oplatin 50mg Injection on the Heart?
You may experience side effects on your heart after taking Oplatin. If this happens, then discontinue its use. Consult your medical practitioner, and do as he/she suggests.
If you are suffering from any of the following diseases, you should not take Oplatin 50mg Injection unless your doctor advises you to do so -
Is this Oplatin 50mg Injection habit forming or addictive?
Forming a habit of Oplatin 50mg Injection has not been reported.
Is it safe to drive or operate heavy machinery when consuming?
You may feel sleepy or tired after taking Oplatin 50mg Injection. So it is best to avoid driving.
Is it safe?
Oplatin 50mg Injection should be used only after doctor's advice.
Is it able to treat mental disorders?
No, Oplatin 50mg Injection is not used to treat mental disorders.
Interaction between Food and Oplatin 50mg Injection
You can take Oplatin 50mg Injection with food.
Interaction between Alcohol and Oplatin 50mg Injection
Consuming Oplatin 50mg Injection with alcohol can have many serious effects on your body.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience