Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Minmek Forte treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Minmek Forte induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Dr. Vedprakash Verma MBBS, MD , Cardiology

Yes, Minmek Forte is safe to use, many people have side effects at first, they usually diminish and then go away completely in a few weeks. A few people find they cannot tolerate metformin, there are other drugs but metformin is usually the first choice. It is very safe

ravi udawat MBBS , General Physician

Minmek Forte should be taken with food to reduce stomach and bowel side effects, which may experience the first few weeks of treatment. Also, exercise regularly and test for sugar in your blood or urine as directed.

Dr. Vipin Khadse MBBS , General Physician

Minmek Forte is not a known cause of alopecia (hair loss). However, the conditions treated by Minmek Forte type 2 diabetes and PCOS, often list hair loss as a possible symptom.

Dr. Ram Saini MD, MBBS , General Physician

Minmek Forte can be taken forever, diabetes is a progressive disease it's possible that more medication and/or insulin may eventually need to be added to the regime.