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Metsafe 500 Tablet SR, a prescription drug, is manufactured in various forms such as Tablet. Primarily, it is used for the treatment of Diabetes.
The right dosage of Metsafe 500 Tablet SR depends on the age, gender, and medical history of the patient. The condition it has been prescribed for, and the route of administration also determine the right dosage. For detailed information on this, read through the dosage section.
Metsafe 500 Tablet SR also has some side effects, the most common being Stomach Upset, Difficulty urinating. While these are the most often observed Metsafe 500 Tablet SR side effects, there are can be others also. These have been listed below. Such side effects of Metsafe 500 Tablet SR normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.
It is also important to note that Metsafe 500 Tablet SR has a Mild effect for pregnant women and Moderate effect on lactating mothers. Further, the section on Metsafe 500 Tablet SR related warnings talks about Metsafe 500 Tablet SR's effects on the liver, heart and kidney.
Metsafe 500 Tablet SR is not recommended if you suffer from certain medical conditions as it can have adverse effects. Congestive Heart Failure (CHF), Anemia, Shock are examples of such conditions. Some other conditions that can be affected by Metsafe 500 Tablet SR are listed in the contraindications section below.
Besides this, Metsafe 500 Tablet SR may also have severe interaction with some medicines. A complete list of these interactions is given below.
In addition to the above precautions for Metsafe 500 Tablet SR, it is important to know that it is safe while driving, and is habit-forming.
Metsafe 500 Tablet SR is used to treat the following -
Main Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
13 - 18 years (Adolescent) |
|
2 - 12 years (Child) |
|
Is the use of Metsafe 500 Tablet SR safe for pregnant women?
Metsafe has mild to no side effects in pregnant women.
Is the use of Metsafe 500 Tablet SR safe during breastfeeding?
Breastfeeding women may feel side effects of Metsafe. If you see any side effects, stop taking Metsafe immediately and talk to your doctor. Take Metsafe again, only after your doctor's advice.
What is the effect of Metsafe 500 Tablet SR on the Kidneys?
Metsafe does not damage the kidneys.
What is the effect of Metsafe 500 Tablet SR on the Liver?
Metsafe is not harmful for the liver.
What is the effect of Metsafe 500 Tablet SR on the Heart?
You can take Metsafe without any fear of damage to the heart.
Metsafe 500 Tablet SR should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Metsafe 500 Tablet SR unless your doctor advises you to do so -
Is this Metsafe 500 Tablet SR habit forming or addictive?
Metsafe 500 Tablet SR does not cause addiction.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can comfortably use machinery or drive after taking Metsafe 500 Tablet SR since it will not make you feel sleepy.
Is it safe?
Metsafe 500 Tablet SR should be used only after doctor's advice.
Is it able to treat mental disorders?
No, Metsafe 500 Tablet SR cannot treat any kind of mental disorder.
Interaction between Food and Metsafe 500 Tablet SR
There is no information on the effects of taking Metsafe 500 Tablet SR with food, because this topic has not been scientifically researched yet.
Interaction between Alcohol and Metsafe 500 Tablet SR
Consult your doctor before consuming alcohol while taking Metsafe 500 Tablet SR as it can have severe side effects.
Yes, Metsafe can cause night sweat, the exact mechanism of sweating is not known. But some research suggests that Metsafe causes hypoglycemia (low blood sugar) especially at night which can cause night sweats. Need to monitor your blood glucose level regularly, and talk to your doctor as your dose of Metsafe may need to be adjusted.
Metsafe can be taken forever, diabetes is a progressive disease it's possible that more medication and/or insulin may eventually need to be added to the regime.
Lactic acidosis associated with Metsafe treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Metsafe induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst.
Metsafe works by decreasing the hepatic glucose production. It also works to lower blood sugar by increasing your sensitivity to insulin and decreasing the amount of glucose that is absorbed from the food you eat.
Yes, Metsafe commonly cause stomach upset like diarrhea, abdominal pain, nausea, and vomiting. To avoid these side effects you should take Metsafe with your meal and increase the dose gradually.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826