Dr. Vipin Khadse MBBS , General Physician

Metlead is not a known cause of alopecia (hair loss). However, the conditions treated by Metlead type 2 diabetes and PCOS, often list hair loss as a possible symptom.

Dr. Bharat MBBS , General Physician

The long-term use can lead to the deficiency of Vitamin B12, which can further lead to megaloblastic anemia. Furthermore, Long-term Metformin use can also lead to kidney and liver problems. 

Dr. Joydeep Sarkar MBBS , Internal Medicine

Yes, Metlead can cause night sweat, the exact mechanism of sweating is not known. But some research suggests that Metlead causes hypoglycemia (low blood sugar) especially at night which can cause night sweats. Need to monitor your blood glucose level regularly, and talk to your doctor as your dose of Metlead may need to be adjusted.

Dr. Rahul Poddar MBBS, DNB, MBBS, DNB , General Surgery

Metlead works by decreasing the hepatic glucose production. It also works to lower blood sugar by increasing your sensitivity to insulin and decreasing the amount of glucose that is absorbed from the food you eat.

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Metlead treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Metlead induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst.