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Macmika 500 Injection, a prescription drug, is manufactured in various forms such as Injection. It is primarily used for the treatment of Urinary Tract Infection. Macmika 500 Injection also has some secondary and off-label uses. These are listed below.
Medical history of the patient along with age and gender determines the dosage of Macmika 500 Injection. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Detailed information has been provided in the dosage section.
Besides the aforementioned side effects, there are other adverse effects of Macmika 500 Injection as well, which are listed below. Such side effects of Macmika 500 Injection normally do not last long and go away once the treatment is completed. Please speak with your doctor if these side effects worsen or persist for a longer duration.
In addition, Macmika 500 Injection's effect is Severe during pregnancy and Unknown for lactating mothers. In addition, Macmika 500 Injection's effects on the liver, heart and kidney are discussed below in the Macmika 500 Injection related warnings section.
Macmika 500 Injection is not recommended if you suffer from certain medical conditions as it can have adverse effects. Dehydration, Parkinson's Disease, Hearing Loss are examples of such conditions. Other conditions have been mentioned below in the Macmika 500 Injection contraindications section.
Besides this, Macmika 500 Injection may also have severe interaction with some medicines. See below for a complete list.
Along with the above-mentioned precautions, remember that taking Macmika 500 Injection is considered safe while driving, and is addictive.
Macmika 500 Injection is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
13 - 18 years (Adolescent) |
|
Infant (1 month to 2 years) |
|
Neonates (0 to 1 month) |
|
2 - 12 years (Child) |
|
Is the use of Macmika 500 Injection safe for pregnant women?
Macmika can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.
Is the use of Macmika 500 Injection safe during breastfeeding?
Due to lack of research work on this topic, the side effects of Macmika for breastfeeding women are not known.
What is the effect of Macmika 500 Injection on the Kidneys?
Use of Macmika may be dangerous for kidney. Do not use it without doctor advice.
What is the effect of Macmika 500 Injection on the Liver?
Macmika is rarely harmful for the liver.
What is the effect of Macmika 500 Injection on the Heart?
Very few cases of side effects of Macmika on the heart have been reported.
Macmika 500 Injection should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
If you are suffering from any of the following diseases, you should not take Macmika 500 Injection unless your doctor advises you to do so -
Is this Macmika 500 Injection habit forming or addictive?
No, there is no any evidence that Macmika 500 Injection is addictive.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can operate a vehicle or heavy machinery after taking Macmika 500 Injection since it does not cause drowsiness.
Is it safe?
Yes, Macmika 500 Injection is safe but you must consult your doctor before taking it.
Is it able to treat mental disorders?
No, Macmika 500 Injection cannot treat any kind of mental disorder.
Interaction between Food and Macmika 500 Injection
Taking Macmika 500 Injection with food is safe.
Interaction between Alcohol and Macmika 500 Injection
No research has been done on this till date. Therefore, it is not known what the effect of taking Macmika 500 Injection with alcohol will be.
Yes, Macmika is nephrotoxic. Nephrotoxicity depends on dose and duration of therapy. Thus, nephrotoxicity is likely to occur if Macmika taken a high dose for a long time or may occur if the drug is given to a patient that already suffer from kidney problem. Nephrotoxicity associated with this drug may reduce or minimize by taking some precaution before consuming this drug like monitor kidney functions regularly and do not take it in high doses. Avoid taking Macmika with another nephrotoxic drug. If you notice any urine discoloration after taking this drug then inform your doctor immediately.
No, Macmika does not cause constipation in patients who are taking it. However, if you are experiencing constipation after taking this drug then inform your doctor and take precautionary methods such as eating fibrous foods to avoid constipation.
Yes, Macmika has been reported to cause diarrhoea and it is a common side effect of this medicine. Drink plenty of fluids while you are taking this medicine. If you are experiencing severe diarrhoea after using this drug, discuss with your doctor immediately without any further delay.
Do not self-administer Macmika. It comes in the form of injection and given preferably 2 - 3 times in a day (Intravenously). Discontinuing the medicine in between may promote resistant bacteria which result in a relapse of the infection. You are recommended to complete the 7 - 10 days course even after getting symptomatic relief. In case you feel any discomfort such as hearing loss and nephrotoxicity while taking Macmika please inform your doctor immediately.
No, Macmika cannot be taken with penicillin. Because penicillin inactivates the Macmika by combining the beta-lactam ring of penicillin with an amino group of this drug to form amide which is biologically inactive. For this reason Macmika should not be taken with penicillin. The chances of inactivation of this drug are higher in case of renal failure because in this case concentration of penicillin is higher in the kidney for a longer time as compared to the normal renal function.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Arikayce (amikacin)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 749
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 136-137