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Glyciphage is a commercial drug that is prescribed in the form of Tablet. It is primarily used for the treatment of Diabetes.
The optimal dosage of Glyciphage is largely dependent on the individual's body weight, medical history, gender and age. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. For detailed information on this, read through the dosage section.
The side effects typically associated with Glyciphage include Stomach Upset, Difficulty urinating. Apart from the aforementioned side effects, Glyciphage can also lead to other problems, which have been listed below. These side effects of Glyciphage are usually temporary and subside with the completion of treatment. If, however, they worsen or do not go away, please speak with your physician.
It is also important to note that Glyciphage has a Mild effect for pregnant women and Moderate effect on lactating mothers. Warnings related to Glyciphage's effects on the liver, heart and kidney, if any, have been listed below.
Glyciphage can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Glyciphage in conditions like Congestive Heart Failure (CHF), Anemia, Shock. Some other conditions that can be affected by Glyciphage are listed in the contraindications section below.
Additionally, Glyciphage may also adversely react with other medicines. See below for a complete list.
Along with the above-mentioned precautions, remember that taking Glyciphage is considered safe while driving, and is addictive.
Glyciphage is used to treat the following -
Main Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
13 - 18 years (Adolescent) |
|
2 - 12 years (Child) |
|
Is the use of Glyciphage safe for pregnant women?
Pregnant women can consume [medicine]. Though Glyciphage has mild side effects when taken during pregnany
Is the use of Glyciphage safe during breastfeeding?
If you are breastfeeding, you may experience some harmful effects of Glyciphage. In case you experience any of these, discontinue its use until you consult your doctor.
What is the effect of Glyciphage on the Kidneys?
Glyciphage does not damage the kidneys.
What is the effect of Glyciphage on the Liver?
Glyciphage is completely safe for the liver.
What is the effect of Glyciphage on the Heart?
Using Glyciphage does not have any harmful effects on the heart.
Glyciphage should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Glyciphage unless your doctor advises you to do so -
Is this Glyciphage habit forming or addictive?
Glyciphage does not cause addiction.
Is it safe to drive or operate heavy machinery when consuming?
Glyciphage will not make you feel sleepy or drowsy. So you drive or operate machinery safely.
Is it safe?
Yes, Glyciphage is safe but you must consult your doctor before taking it.
Is it able to treat mental disorders?
There is no benefit of taking Glyciphage for mental disorders.
Interaction between Food and Glyciphage
There isn't any research available on the side effects of taking Glyciphage with food.
Interaction between Alcohol and Glyciphage
Consuming Glyciphage with alcohol can have many serious effects on your body.
Glyciphage can be taken forever, diabetes is a progressive disease it's possible that more medication and/or insulin may eventually need to be added to the regime.
Glyciphage works by decreasing the hepatic glucose production. It also works to lower blood sugar by increasing your sensitivity to insulin and decreasing the amount of glucose that is absorbed from the food you eat.
The long-term use can lead to the deficiency of Vitamin B12, which can further lead to megaloblastic anemia. Furthermore, Long-term Metformin use can also lead to kidney and liver problems.
Glyciphage should be taken with food to reduce stomach and bowel side effects, which may experience the first few weeks of treatment. Also, exercise regularly and test for sugar in your blood or urine as directed.
Lactic acidosis associated with Glyciphage treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Glyciphage induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826