Glyciphage

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Glyciphage Information

Glyciphage is a commercial drug that is prescribed in the form of Tablet. It is primarily used for the treatment of Diabetes.

The optimal dosage of Glyciphage is largely dependent on the individual's body weight, medical history, gender and age. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. For detailed information on this, read through the dosage section.

The side effects typically associated with Glyciphage include Stomach Upset, Difficulty urinating. Apart from the aforementioned side effects, Glyciphage can also lead to other problems, which have been listed below. These side effects of Glyciphage are usually temporary and subside with the completion of treatment. If, however, they worsen or do not go away, please speak with your physician.

It is also important to note that Glyciphage has a Mild effect for pregnant women and Moderate effect on lactating mothers. Warnings related to Glyciphage's effects on the liver, heart and kidney, if any, have been listed below.

Glyciphage can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Glyciphage in conditions like Congestive Heart Failure (CHF), Anemia, Shock. Some other conditions that can be affected by Glyciphage are listed in the contraindications section below.

Additionally, Glyciphage may also adversely react with other medicines. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Glyciphage is considered safe while driving, and is addictive.


Glyciphage Benefits & Uses

Glyciphage is used to treat the following -

Main Benefits

Glyciphage Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Diabetes Type 2
  • Before or After Meal: With meal
  • Single Maximum Dose: 500 mg
  • Dosage Form: Tablet (Immediate Release)
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Glyciphage Side Effects

Based on research, the following side effects have been observed when Glyciphage is used -

Severe

  • Blurred vision

Moderate

Mild

  • Nausea or vomiting
  • Altered taste
  • Diarrhoea
  • पेट दर्द
  • Loss of appetite
  • Headache
  • पेट की गैस
  • Dyspepsia

Common

  • Stomach Upset
  • Difficulty urinating

Glyciphage Related Warnings

  • Is the use of Glyciphage safe for pregnant women?


    Pregnant women can consume [medicine]. Though Glyciphage has mild side effects when taken during pregnany

    Mild
  • Is the use of Glyciphage safe during breastfeeding?


    If you are breastfeeding, you may experience some harmful effects of Glyciphage. In case you experience any of these, discontinue its use until you consult your doctor.

    Moderate
  • What is the effect of Glyciphage on the Kidneys?


    Glyciphage does not damage the kidneys.

    Safe
  • What is the effect of Glyciphage on the Liver?


    Glyciphage is completely safe for the liver.

    Safe
  • What is the effect of Glyciphage on the Heart?


    Using Glyciphage does not have any harmful effects on the heart.

    Safe

Severe Interaction of Glyciphage with Other Drugs

Glyciphage should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Glyciphage Contraindications

If you are suffering from any of the following diseases, you should not take Glyciphage unless your doctor advises you to do so -


Frequently asked Questions about Glyciphage

  • Is this Glyciphage habit forming or addictive?


    Glyciphage does not cause addiction.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Glyciphage will not make you feel sleepy or drowsy. So you drive or operate machinery safely.

    Safe
  • Is it safe?


    Yes, Glyciphage is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Glyciphage for mental disorders.

    No

Glyciphage Interactions with Food and Alcohol

  • Interaction between Food and Glyciphage


    There isn't any research available on the side effects of taking Glyciphage with food.

    Unknown
  • Interaction between Alcohol and Glyciphage


    Consuming Glyciphage with alcohol can have many serious effects on your body.

    Severe

Frequently asked Questions about Glyciphage

Question almost 6 years ago

How long should I take Glyciphage for?

Dr. Ram Saini MD, MBBS , General Physician

Glyciphage can be taken forever, diabetes is a progressive disease it's possible that more medication and/or insulin may eventually need to be added to the regime. 

Question over 5 years ago

How does Glyciphage increase lactic acidosis?

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Glyciphage treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Glyciphage induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Question over 5 years ago

How does Glyciphage work for PCOS?

Dr. Sameer Awadhiya MBBS , Pediatrics

Glyciphage increases the sensitivity of insulin, young women with PCOS often have elevated insulin levels and are more likely to develop diabetes. It is often prescribed for women with PCOS to help prevent diabetes. A lifestyle that includes healthy nutrition and daily exercise is the most important part of a PCOS treatment plan.

Question almost 6 years ago

Does Glyciphage cause sleep problems?

Dr. Ayush Pandey MBBS, PG Diploma , General Physician

Yes, Glyciphage can cause some sleep problems, especially insomnia. On the other hand, Glyciphage has proven to be useful for preventing sleep apnea. The exact relationship between Glyciphage and sleep problems is still not clear, and further studies are needed for a clearer understanding.

Question over 5 years ago

Can I take Glyciphage with statin?

Dr. R.K Singh MBBS , Diabetology

Yes, Glyciphage can be taken with the statin. There is no serious or harmful interaction have been observed between them. Some studies say that it's possible your blood sugar (blood glucose) level may increase when you take a statin, which may lead to developing type 2 diabetes. The risk is small but important enough that the Food and Drug Administration (FDA) has issued a warning on statin labels regarding blood glucose levels and diabetes.


See all substitutes for Glyciphage


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826

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