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Glyciphage P is a prescription drug, available for use as Tablet. Secondary and off-label uses of Glyciphage P have also been mentioned below.
The correct dosage of Glyciphage P depends on the patient's age, gender, and medical history. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Refer to the dosage section for a detailed discussion.
Glyciphage P also has some side effects, the most common being Stomach Upset, Difficulty urinating, Muscle Ache. Some other side effects of Glyciphage P have been listed ahead. Such side effects of Glyciphage P normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.
In addition, Glyciphage P's effect is Moderate during pregnancy and Moderate for lactating mothers. Further, the section on Glyciphage P related warnings talks about Glyciphage P's effects on the liver, heart and kidney.
Glyciphage P is contraindicated in people with pre-existing medical conditions like Congestive Heart Failure (CHF), Anemia, Shock as it can result in adverse effects. Other conditions have been mentioned below in the Glyciphage P contraindications section.
Drug reaction of Glyciphage P with other medicines has been reported. A complete list of these interactions is given below.
Along with the above-mentioned precautions, remember that taking Glyciphage P is considered safe while driving, and is addictive.
Glyciphage P is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
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Geriatric |
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Is the use of Glyciphage P safe for pregnant women?
Glyciphage P can have harmful effects in pregnant women. If you experience any discomfort after using Glyciphage P, then discontinue the use and take your doctor's advice.
Is the use of Glyciphage P safe during breastfeeding?
Breastfeeding women may feel side effects of Glyciphage P. If you see any side effects, stop taking Glyciphage P immediately and talk to your doctor. Take Glyciphage P again, only after your doctor's advice.
What is the effect of Glyciphage P on the Kidneys?
Glyciphage P has very mild side effects on the kidneys.
What is the effect of Glyciphage P on the Liver?
You may experience side effects on your liver after taking Glyciphage P. If this happens, then discontinue its use. Consult your medical practitioner, do as he/she suggests.
What is the effect of Glyciphage P on the Heart?
Glyciphage P may cause harmful effects on the heart. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.
Glyciphage P should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Glyciphage P unless your doctor advises you to do so -
Is this Glyciphage P habit forming or addictive?
Forming a habit of Glyciphage P has not been reported.
Interaction between Food and Glyciphage P
There is no information on the effects of taking Glyciphage P with food, because this topic has not been scientifically researched yet.
Interaction between Alcohol and Glyciphage P
Chances of side effects of drinking alcohol while taking Glyciphage P are low. If you feel any adverse effects, please seek medical advice as soon as possible.
Yes, Glyciphage P commonly cause stomach upset like diarrhea, abdominal pain, nausea, and vomiting. To avoid these side effects you should take Glyciphage P with your meal and increase the dose gradually.
Glyciphage P helps in weight loss by reducing appetite and food intake. It also increases the insulin sensitivity in your body to work more effectively. This lead to decreased glucose production increases the use of glucose and decrease the fat deposition further helps in weight loss. However, Glyciphage P is not approved for weight loss, this is an off-label use.
Yes, you can take Glyciphage P with a beta-blocker. People with diabetes tend to develop heart disease or stroke at an earlier age than the general population. One reason for this is that high glucose levels increase your risk of high blood pressure (hypertension). No harmful interactions are seen between them. However, a recent study suggests that beta-blockers can decrease the plasma level of Glyciphage P and long-term use can increase lactic acid and uric acid in the blood.
Lactic acidosis associated with Glyciphage P treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Glyciphage P induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst.
Glyciphage P is used with a proper diet and exercise program, to treat diabetes. It is also used with other medication to reduce the high blood sugar. It is used in a patient with type2 diabetes. It is also used in the treatment of polycystic ovarian syndrome (PCOS) and cancer.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Glucophage® (metformin hydrochloride)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 275-276
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 825-826
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Actos (pioglitazone hydrochloride)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 276-277
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1032-1033