Dr. Sameer Awadhiya MBBS , Pediatrics

Etformin increases the sensitivity of insulin, young women with PCOS often have elevated insulin levels and are more likely to develop diabetes. It is often prescribed for women with PCOS to help prevent diabetes. A lifestyle that includes healthy nutrition and daily exercise is the most important part of a PCOS treatment plan.

Dr. Manoj Meena MBBS , General Physician

Lactic acidosis associated with Etformin treatment is a rare but fatal adverse effect. Lactic acidosis appears to result from biguanide interference causing an increase in production and decrease in clearance of lactate leading to higher cellular lactate levels. A decrease in pyruvate carboxylase activity, the rate-limiting enzyme in the formation of glucose from lactate, can also decrease hepatic metabolism of lactate. leading to increasing lactic acidosis. Signs and symptoms of Etformin induced lactic acidosis are nonspecific and include anorexia, nausea, vomiting, altered level of consciousness, hyperpnoea, abdominal pain, and thirst. 

Dr. Ram Saini MD, MBBS , General Physician

Etformin can be taken forever, diabetes is a progressive disease it's possible that more medication and/or insulin may eventually need to be added to the regime. 

Dr. Manju Shekhawat MBBS , General Physician

No, you should not take alcohol with Etformin, because it can cause serious side effects which includes hypoglycemia (low blood sugar). The risk of hypoglycemia is higher when you're drinking and taking Etformin than if you're just taking Etformin. Some of the signs of hypoglycemia include dizziness, confusion, and drowsiness.

Dr. Sameer Awadhiya MBBS , Pediatrics

Yes, you can take Etformin with a beta-blocker. People with diabetes tend to develop heart disease or stroke at an earlier age than the general population. One reason for this is that high glucose levels increase your risk of high blood pressure (hypertension). No harmful interactions are seen between them. However, a recent study suggests that beta-blockers can decrease the plasma level of Etformin and long-term use can increase lactic acid and uric acid in the blood.