Combivir

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Combivir Information

Combivir is a prescription drug, available for use as Tablet. Secondary and off-label uses of Combivir have also been mentioned below.

The optimal dosage of Combivir is largely dependent on the individual's body weight, medical history, gender and age. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Refer to the dosage section for a detailed discussion.

Besides the aforementioned side effects, there are other adverse effects of Combivir as well, which are listed below. Normally, these side effects of Combivir are not long lasting and go away when the treatment is finished. Please speak with your doctor if these side effects worsen or persist for a longer duration.

It is also important to note that Combivir has a Moderate effect for pregnant women and Moderate effect on lactating mothers. Warnings related to Combivir's effects on the liver, heart and kidney, if any, have been listed below.

Combivir is not recommended if you suffer from certain medical conditions as it can have adverse effects. Kidney Disease, Pancreatitis, Kidney Disease are examples of such conditions. Other contraindications of Combivir have been discussed in the sections ahead.

Additionally, Combivir may also adversely react with other medicines. Refer to the list below for further details.

Along with the above-mentioned precautions, remember that taking Combivir is considered not safe while driving, and is not addictive.


Combivir Benefits & Uses

Combivir is used to treat the following -

Other Benefits

Combivir Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
13 - 18 years (Adolescent)
  • Disease: HIV/AIDS (Acquired Immunodeficiency Syndrome)
  • Before or After Meal: Either
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 150 mg lamivudine and 300 mg zidovudine
2 - 12 years (Child)
  • Disease: HIV/AIDS (Acquired Immunodeficiency Syndrome)
  • Before or After Meal: Either
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 150 mg lamivudine and 300 mg zidovudine, patients having above 30 kg weight can take only
Adult
  • Disease: HIV/AIDS (Acquired Immunodeficiency Syndrome)
  • Before or After Meal: Either
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 150 mg lamivudine and 300 mg zidovudine
Geriatric
  • Disease: HIV/AIDS (Acquired Immunodeficiency Syndrome)
  • Before or After Meal: Either
  • Single Maximum Dose: 1 Tablet
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: strength 150 mg lamivudine and 300 mg zidovudine

Combivir Related Warnings

  • Is the use of Combivir safe for pregnant women?


    Combivir may have some side effects during pregnancy. Pregnant women should discontinue the use of Combivir, and talk to their doctor, if they notice any discomfort.

  • Is the use of Combivir safe during breastfeeding?


    Breastfeeding women may feel side effects of Combivir. If you see any side effects, stop taking Combivir immediately and talk to your doctor. Take Combivir again, only after your doctor's advice.

  • What is the effect of Combivir on the Kidneys?


    Combivir rarely affects the kidneys.

  • What is the effect of Combivir on the Liver?


    Side effects of Combivir rarely affect the liver.

  • What is the effect of Combivir on the Heart?


    Combivir may have mild side effects on the heart. Most people will never see any effect on the heart.


Severe Interaction of Combivir with Other Drugs

Combivir should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

Mild

Sulfamethoxazole,Trimethoprim
    Fluconazole

    Combivir Contraindications

    If you are suffering from any of the following diseases, you should not take Combivir unless your doctor advises you to do so -


    Frequently asked Questions about Combivir

    • Is this Combivir habit forming or addictive?


      No, there is no any evidence that Combivir is addictive.

    Combivir Interactions with Food and Alcohol

    • Interaction between Food and Combivir


      Taking Combivir with food does not cause any problems.

    • Interaction between Alcohol and Combivir


      Taking alcohol with Combivir can be dangerous.


    See all substitutes for Combivir


    This medicine data has been created by -

    Vikas Chauhan
    B.Pharma, Pharmacy
    5 Years of Experience

    References

    US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Epivir (lamivudine)

    KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 807-808

    April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 96-99

    US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Retrovir® (zidovudine)

    KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 806-807

    April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1286-1288

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