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Brukin is a prescription medicine that is available as a Injection. It is typically used for the treatment of Urinary Tract Infection. Secondary and off-label uses of Brukin have also been mentioned below.
The right dosage of Brukin depends on the age, gender, and medical history of the patient. The condition it has been prescribed for, and the route of administration also determine the right dosage. For detailed information on this, read through the dosage section.
Some other side effects of Brukin have been listed ahead. Normally, these side effects of Brukin are not long lasting and go away when the treatment is finished. Consult your doctor if these side effects become worse or stay for a longer duration.
In addition, Brukin's effect is Severe during pregnancy and Unknown for lactating mothers. In addition, Brukin's effects on the liver, heart and kidney are discussed below in the Brukin related warnings section.
Brukin is not recommended if you suffer from certain medical conditions as it can have adverse effects. Dehydration, Parkinson's Disease, Hearing Loss are examples of such conditions. Some other conditions that can be affected by Brukin are listed in the contraindications section below.
Besides this, Brukin may also have severe interaction with some medicines. See below for a complete list.
You should also be aware that Brukin is safe while driving, and is addiction.
Brukin is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
|
Geriatric |
|
13 - 18 years (Adolescent) |
|
Infant (1 month to 2 years) |
|
Neonates (0 to 1 month) |
|
2 - 12 years (Child) |
|
Is the use of Brukin safe for pregnant women?
Brukin can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.
Is the use of Brukin safe during breastfeeding?
In the absence of any scientific study about the side effects of Brukin in breastfeeding women, information on safety of Brukin is unavailable.
What is the effect of Brukin on the Kidneys?
Consumption of Brukin can harm the kidneys. So it is important to take medical advice beforehand.
What is the effect of Brukin on the Liver?
Very few cases of side effects of Brukin on the liver have been reported.
What is the effect of Brukin on the Heart?
Side effects of Brukin rarely affect the heart.
Brukin should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
If you are suffering from any of the following diseases, you should not take Brukin unless your doctor advises you to do so -
Is this Brukin habit forming or addictive?
No, there is no any evidence that Brukin is addictive.
Is it safe to drive or operate heavy machinery when consuming?
Yes, it is safe to do these activities or work after taking Brukin as it does not make you drowsy.
Is it safe?
Brukin should be used only after doctor's advice.
Is it able to treat mental disorders?
There is no benefit of taking Brukin for mental disorders.
Interaction between Food and Brukin
Taking Brukin with food does not cause any problems.
Interaction between Alcohol and Brukin
It is difficult to say anything about the effect of Brukin and alcohol. No research has been done on this yet.
Yes, Brukin has been reported to cause ototoxicity (hearing loss or deafness) which is irreversible and may progress after discontinuation of the drug. It is a common side effect of this medicine. If you experience hearing loss or deafness after consuming or applying for this medicine, then consult your doctor and follow his/her instructions.
Yes, Brukin is nephrotoxic. Nephrotoxicity depends on dose and duration of therapy. Thus, nephrotoxicity is likely to occur if Brukin taken a high dose for a long time or may occur if the drug is given to a patient that already suffer from kidney problem. Nephrotoxicity associated with this drug may reduce or minimize by taking some precaution before consuming this drug like monitor kidney functions regularly and do not take it in high doses. Avoid taking Brukin with another nephrotoxic drug. If you notice any urine discoloration after taking this drug then inform your doctor immediately.
Yes, Brukin is effective against bacteria (Pseudomonas). But it is also found that Pseudomonas can get resistant to this drug and in that case Brukin will not produce desired results. If you are experiencing no symptomatic relief after taking this medicine then inform your doctor and follow his/her instructions.
Brukin is a broad-spectrum antibiotic which is active against both Gram-positive and Gram-negative bacteria. It works by preventing the synthesis of proteins that bacteria need to survive, in the absence of protein synthesis bacteria become vulnerable and dies. It is effective against different types of bacteria such as Escherichia coli, Proteus species, S. aureus, Acinetobacter and Serratia species.
No, Brukin cannot be taken with penicillin. Because penicillin inactivates the Brukin by combining the beta-lactam ring of penicillin with an amino group of this drug to form amide which is biologically inactive. For this reason Brukin should not be taken with penicillin. The chances of inactivation of this drug are higher in case of renal failure because in this case concentration of penicillin is higher in the kidney for a longer time as compared to the normal renal function.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Arikayce (amikacin)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 749
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 136-137