Brimolol Information

Brimolol is a prescription drug, available for use as Drops. Other than this, Brimolol has some other therapeutic uses, which have been discussed ahead.

Medical history of the patient along with age and gender determines the dosage of Brimolol. The condition it has been prescribed for, and the route of administration also determine the right dosage. Refer to the dosage section for a detailed discussion.

The most common side effects of Brimolol are Eye Burning, Eye irritation, Stinging in the Eyes. Besides the aforementioned side effects, there are other adverse effects of Brimolol as well, which are listed below. Normally, these side effects of Brimolol are not long lasting and go away when the treatment is finished. Consult your doctor if these side effects become worse or stay for a longer duration.

Furthermore, you should know that effect of Brimolol is Mild for pregnant women and Unknown for women who are breastfeeding. It is important to know if Brimolol has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Brimolol related warnings section.

Brimolol can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Brimolol in conditions like Heart Failure, Diabetes, COPD (Chronic Obstructive Pulmonary Disease). Some other conditions that can be affected by Brimolol are listed in the contraindications section below.

Drug reaction of Brimolol with other medicines has been reported. See below for a complete list.

In addition to these precautions, you may also note that Brimolol is safe while driving, and is is addictive in nature.

Brimolol Benefits & Uses
Brimolol Dosage & How to Take
Brimolol Side Effects
Brimolol Related Warnings
Severe Interaction of Brimolol with Other Drugs
Brimolol Contraindications
Frequently asked Questions about Brimolol
Brimolol Interactions with Food and Alcohol

Brimolol Benefits & Uses

Brimolol is used to treat the following -

Other Benefits

Glaucoma

Brimolol Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group	Dosage
13 - 18 years (Adolescent)	Disease: Glaucoma Before or After Meal: As advised by a physician Single Maximum Dose: 1 drop Dosage Route: Ophthalmic Frequency: 2 daily Course Duration: As directed by the doctor Special Instructions: Dosage strength: Timolol (0.5%) Brimonidine (0.2%)
2 - 12 years (Child)	Disease: Glaucoma Before or After Meal: As advised by a physician Single Maximum Dose: 1 drop Dosage Route: Ophthalmic Frequency: 2 daily Course Duration: As directed by the doctor Special Instructions: Dosage strength: Timolol (0.5%) Brimonidine (0.2%)
Adult	Disease: Glaucoma Before or After Meal: As advised by a physician Single Maximum Dose: 1 drop Dosage Route: Ophthalmic Frequency: 2 daily Course Duration: As directed by the doctor Special Instructions: Dosage strength: Timolol (0.5%) Brimonidine (0.2%)
Geriatric	Disease: Glaucoma Before or After Meal: As advised by a physician Single Maximum Dose: 1 drop Dosage Route: Ophthalmic Frequency: 2 daily Course Duration: As directed by the doctor Special Instructions: Dosage strength: Timolol (0.5%) Brimonidine (0.2%)

Brimolol Related Warnings

Is the use of Brimolol safe for pregnant women?

Pregnant women can consume [medicine]. Though Brimolol has mild side effects when taken during pregnany
Is the use of Brimolol safe during breastfeeding?

No research work has been carried out till date on effect of Brimolol on breastfeeding women. So it is not known whether taking Brimolol will cause side effects or not.
What is the effect of Brimolol on the Kidneys?

Kidney can be affected by Brimolol. If you experience any unwanted effects of this drug, stop taking it. You should take it again only after medical advice.
What is the effect of Brimolol on the Liver?

Brimolol may cause harmful effects on liver. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.
What is the effect of Brimolol on the Heart?

Brimolol can have moderate side effects on the heart. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

Severe Interaction of Brimolol with Other Drugs

Brimolol should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate

Epinephrine

Alemtuzumab

Amlodipine

Amiodarone

Glipizide,Metformin

Amace Tablet

Glibenclamide,Metformin

Chlorpheniramine,Dextromethorphan,Paracetamol,Phenylephrine

Midazolam

Diazepam

Flurazepam

Digoxin

Linezolid

Rasagiline

Amitriptyline

Brimolol Contraindications

If you are suffering from any of the following diseases, you should not take Brimolol unless your doctor advises you to do so -

Heart Failure
Diabetes
COPD (Chronic Obstructive Pulmonary Disease)
Asthma
Kidney Disease
Liver Disease
Heart Disease
Depression
Kidney Disease
Liver Disease

Frequently asked Questions about Brimolol

Is this Brimolol habit forming or addictive?

No, there is no any evidence that Brimolol is addictive.

Brimolol Interactions with Food and Alcohol

Interaction between Food and Brimolol

It is safe to take Brimolol with food.
Interaction between Alcohol and Brimolol

Information about the interaction of Brimolol and alcohol is not currently available because this topic has not been researched yet.

See all substitutes for Brimolol

Iotim B Ophthalmic Solution - ₹336
Combigan Opthalmic Solution - ₹472
Britiblu Eye Drop - ₹167
Betabrim Eye Drop - ₹299
Briopt Eye Drop - ₹299
Brimocom Eye Drop - ₹370
Brimolol Eye Drop - ₹383
Bidin T Eye Drop - ₹200
Abpress Eye Drop - ₹255
Brimotim Eye Drop - ₹115
Brimofinet 5/1.5 Eye Drop - ₹150
Brimochek T Eye Drop - ₹343
Globrim T Eye Drop - ₹90
Brimonidine + Timolol Eye Drop - ₹440
Cibrim T Eye Drop - ₹130
StayHappi Brimonidine Tartrate 0.2% + Timolol 0.5% Eye Drop - ₹84
Brimotus Eye Drop - ₹161
Apbidin Tm Eye Drops - ₹155
Glubrim Eye Drop - ₹200
Alfaprest T Eye Drop - ₹165

This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Istalol® (timolol maleate ophthalmic solution)

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1401

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 153

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1405

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 154

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Alphagan® (brimonidine tartrate)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Simbrinza™ (brinzolamide/brimonidine tartrate)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Enidin® (brimonidine tartrate)

Therapeutic Goods Administration (TGA): Department of Health [Internet]. Governmet of Australia; Package leaflet information for the user; Alphagan® P (brimonidine tartrate)

Brimolol Eye Drop