Axanthine

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Axanthine Information

Axanthine is a prescription drug, available for use as Tablet. Primarily, it is used for the treatment of Gout, High Uric Acid Levels in the Blood. Secondary and off-label uses of Axanthine have also been mentioned below.

The correct dosage of Axanthine depends on the patient's age, gender, and medical history. Besides the medical condition it is advised for, the route of administration also plays an important role in determining the correct drug dosage. Refer to the dosage section for a detailed discussion.

While these are the most often observed Axanthine side effects, there are can be others also. These have been listed below. Normally, these side effects of Axanthine are not long lasting and go away when the treatment is finished. Consult your doctor if these side effects become worse or stay for a longer duration.

It is also important to note that Axanthine has a Severe effect for pregnant women and Mild effect on lactating mothers. Warnings related to Axanthine's effects on the liver, heart and kidney, if any, have been listed below.

Other contraindications of Axanthine have been discussed in the sections ahead.

Drug interactions for Axanthine have been reported in the medical literature. See below for a complete list.

Along with the above-mentioned precautions, remember that taking Axanthine is considered safe while driving, and is addictive.


Axanthine Benefits & Uses

Axanthine is used to treat the following -

Other Benefits

Axanthine Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Gout
  • Before or After Meal: After Meal
  • Single Maximum Dose: 300 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Gout
  • Before or After Meal: After Meal
  • Single Maximum Dose: 300 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Gout
  • Before or After Meal: After Meal
  • Single Maximum Dose: 100 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dose may increase up to 300 mg
2 - 12 years (Child)
  • Disease: High Uric Acid Levels in the Blood
  • Before or After Meal: After Meal
  • Single Maximum Dose: 100 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Axanthine Related Warnings

  • Is the use of Axanthine safe for pregnant women?


    Axanthine shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Axanthine safe during breastfeeding?


    Side effects of Axanthine on breastfeeding women are very mild.

    Mild
  • What is the effect of Axanthine on the Kidneys?


    Kidney can be affected by Axanthine. If you experience any unwanted effects of this drug, stop taking it. You should take it again only after medical advice.

    Moderate
  • What is the effect of Axanthine on the Liver?


    Axanthine can have moderate side effects on the liver. If you notice any harmful effects then stop taking this drug right away. Consult your doctor before using this medicine again.

    Moderate
  • What is the effect of Axanthine on the Heart?


    Side effects of Axanthine rarely affect the heart.

    Mild

Severe Interaction of Axanthine with Other Drugs

Axanthine should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Axanthine Contraindications

If you are suffering from any of the following diseases, you should not take Axanthine unless your doctor advises you to do so -


Frequently asked Questions about Axanthine

  • Is this Axanthine habit forming or addictive?


    Axanthine is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can operate a vehicle or heavy machinery after taking Axanthine since it does not cause drowsiness.

    Safe
  • Is it safe?


    Axanthine is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Axanthine in mental disorders is not effective.

    No

Axanthine Interactions with Food and Alcohol

  • Interaction between Food and Axanthine


    Axanthine may take longer to act if you eat some foods while taking it. Follow your doctor's advice on this.

    Mild
  • Interaction between Alcohol and Axanthine


    Consumption of alcohol and Axanthine together may have severe effects on your health.

    Severe

Frequently asked Questions about Axanthine

Question over 5 years ago

Does Axanthine cause drowsiness?

Dr. Surender Kumar MBBS , General Physician

Yes, Axanthine may cause drowsiness or sleepiness. It is the most common side effect of this drug. Activities such as driving and operating heavy machinery should be avoided after taking this Axanthine to prevent accidents and injuries as it causes drowsiness.

Question about 5 years ago

Does Axanthine raise blood sugar levels?

Dr. Sangita Shah MBBS , General Physician

No, Axanthine does not raise or elevate blood sugar (hyperglycemia). It has not been reported by the patients who are taking this drug. If you notice high blood sugar levels after taking this drug, then discuss it with your doctor who might change the dosage of your current medications.

Question almost 6 years ago

What is Axanthine?

Dr. Amit Singh MBBS , General Physician

Axanthine is a brand name of allopurinol and it comes in the form of a tablet (solid unit dosage form). It is an antigout agent that belongs to the class of drugs known as xanthine oxidase inhibitors. It is a prescription drug that is used in the treatment of gout (arthritis that causes intense pain and redness in the joints due to deposition of uric acid crystals). Apart from the treatment of gout Axanthine is given in hyperuricemia and Chemotherapy-induced hyperuricemia (abnormally high levels of uric acid in the blood). It is also given in the treatment of kidney stones.

Question over 5 years ago

Can Axanthine cause diarrhoea?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

Yes, Axanthine has been reported to causes diarrhoea but this occurs in those cases who are taking more than the recommended doses. Drink plenty of fluids while you are taking this medicine. If you are experiencing severe diarrhoea after taking this drug, discuss it with your doctor immediately without any further delay.

Question almost 6 years ago

How does Axanthine work?

Dr. Anand Singh MBBS , General Physician

Axanthine contains allopurinol that belongs to the class of drugs known as xanthine oxidase inhibitors. It works by inhibiting the xanthine oxidase enzyme (Responsible for uric acid production in our body) that lead to disruption in the biosynthesis of uric acid due to which its abnormally high levels are decreased in the body. The decreased levels of uric acid prevent the formation of uric acid crystals and calcium oxalate crystals. Hence, in this way, it prevents from gout.


See all substitutes for Axanthine


This medicine data has been created by -

Vikas Chauhan
B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zyloprim ® (allopurinol)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 216-217

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 125-127

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