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Amine, a prescription drug, is manufactured in various forms such as Injection. It is typically used for the treatment of Urinary Tract Infection. Secondary and off-label uses of Amine have also been mentioned below.
The optimal dosage of Amine is largely dependent on the individual's body weight, medical history, gender and age. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Detailed information has been provided in the dosage section.
Apart from the aforementioned side effects, Amine can also lead to other problems, which have been listed below. Normally, these side effects of Amine are not long lasting and go away when the treatment is finished. Consult your doctor if these side effects become worse or stay for a longer duration.
Furthermore, you should know that effect of Amine is Severe for pregnant women and Unknown for women who are breastfeeding. Further, the section on Amine related warnings talks about Amine's effects on the liver, heart and kidney.
Amine is not recommended if you suffer from certain medical conditions as it can have adverse effects. Dehydration, Parkinson's Disease, Hearing Loss are examples of such conditions. Other contraindications of Amine have been discussed in the sections ahead.
Besides this, Amine may also have severe interaction with some medicines. See below for a complete list.
Along with the above-mentioned precautions, remember that taking Amine is considered safe while driving, and is addictive.
Amine is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Is the use of Amine safe for pregnant women?
Pregnant women may get severe side effects after taking Amine. If you are pregnant, do not take Amine without a doctor's advice.
Is the use of Amine safe during breastfeeding?
In the absence of any scientific study about the side effects of Amine in breastfeeding women, information on safety of Amine is unavailable.
What is the effect of Amine on the Kidneys?
Consumption of Amine can harm the kidneys. So it is important to take medical advice beforehand.
What is the effect of Amine on the Liver?
Very few cases of side effects of Amine on the liver have been reported.
What is the effect of Amine on the Heart?
Amine has very mild side effects on the heart.
Amine should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
If you are suffering from any of the following diseases, you should not take Amine unless your doctor advises you to do so -
Is this Amine habit forming or addictive?
No, you will not get addicted to Amine.
Is it safe to drive or operate heavy machinery when consuming?
Yes, it is safe to do these activities or work after taking Amine as it does not make you drowsy.
Is it safe?
Yes, but consume Amine only on doctor's advice.
Is it able to treat mental disorders?
No, Amine cannot treat any kind of mental disorder.
Interaction between Food and Amine
Taking Amine with food does not cause any problems.
Interaction between Alcohol and Amine
Information about the interaction of Amine and alcohol is not currently available because this topic has not been researched yet.
Yes, Amine has been reported to cause ototoxicity (hearing loss or deafness) which is irreversible and may progress after discontinuation of the drug. It is a common side effect of this medicine. If you experience hearing loss or deafness after consuming or applying for this medicine, then consult your doctor and follow his/her instructions.
No, Amine cannot be taken with penicillin. Because penicillin inactivates the Amine by combining the beta-lactam ring of penicillin with an amino group of this drug to form amide which is biologically inactive. For this reason Amine should not be taken with penicillin. The chances of inactivation of this drug are higher in case of renal failure because in this case concentration of penicillin is higher in the kidney for a longer time as compared to the normal renal function.
Yes, Amine is effective against bacteria (Pseudomonas). But it is also found that Pseudomonas can get resistant to this drug and in that case Amine will not produce desired results. If you are experiencing no symptomatic relief after taking this medicine then inform your doctor and follow his/her instructions.
Yes, Amine is nephrotoxic. Nephrotoxicity depends on dose and duration of therapy. Thus, nephrotoxicity is likely to occur if Amine taken a high dose for a long time or may occur if the drug is given to a patient that already suffer from kidney problem. Nephrotoxicity associated with this drug may reduce or minimize by taking some precaution before consuming this drug like monitor kidney functions regularly and do not take it in high doses. Avoid taking Amine with another nephrotoxic drug. If you notice any urine discoloration after taking this drug then inform your doctor immediately.
Yes, Amine is safe to use, if taken in prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as decreased urination, itching, irritation, and hearing loss. If you experience above-mentioned side after consuming this medicine then inform your doctor and follow his/her instructions.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Arikayce (amikacin)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 749
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 136-137