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Scientists discover potential cause of Alzheimer's disease: a mutation in MARK4 enzyme
शेयर करें
October 26, 2020
संदर्भ
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Tokyo Metropolitan University via EurekAlert [Internet]. News release: Cause of Alzheimer's disease traced to mutation in common enzyme, 24 October 2020.
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Sun Y., Sommerville N.R., Liu J.Y.H., Ngan M.P., Poon D., Ponomarev E.D., Lu Z., Kung J.S.C., Rudd J.A.. Intra‐gastrointestinal amyloid‐β1–42 oligomers perturb enteric function and induce Alzheimer's disease pathology. The Journal of Physiology, 1 October 2020; 598(19): 4209-4223. First published 2 July 2020.
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GBD 2016 Dementia Collaborators. Global, regional, and national burden of Alzheimer's disease and other dementias, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016, The Lancet Neurology, 1 January 2019; 18(1): 88-106.
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Oba T., Saito T., Asada A., Shimizu S., Iijima K.M. and Ando K. Microtubule Affinity Regulating Kinase 4 with an Alzheimer's disease-related mutation promotes tau accumulation and exacerbates neurodegeneration, The Journal of Biological Chemistry, 5 October 2020. Epub ahead of print. PMID: 33020179.