What is Yeast allergy test? 

Yeasts are single-celled fungi that can only be seen under a microscope. Many species of yeast, especially those that belong to the Saccharomyces species are widely used in the food industry. Saccharomyces is used to prepare bread, biscuits, alcohol and vinegar among other things.

If you are allergic to yeast, you would not be able to consume any of these foods. This test is done to check whether a person has a sensitivity to yeast or yeast extracts.

Although yeast allergy is not very common, it can cause considerable discomfort in the gastrointestinal tract.

Sensitivity to yeast is detected by a skin prick test or by measuring the number of IgE antibodies against yeast in your bloodstream. Antibodies are proteins that are produced by our immune system to protect the body from harmful foreign substances; IgE antibodies are specifically produced in response to an allergen (a substance that can trigger an allergic reaction in the body).

Some foods that can worsen the symptoms of yeast sensitivity are:

  1. Why is Yeast allergy test performed?
  2. How do you prepare for Yeast allergy test?
  3. How is Yeast allergy test performed?
  4. What do Yeast allergy test results mean?

Your doctor may perform this test to check for yeast sensitivity if you show symptoms of food allergy. Yeast intolerance is a milder form of yeast sensitivity and its symptoms are largely limited to the gastrointestinal tract, however, yeast allergy symptoms are more systemic and may include:

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You do not need any special preparation for this test. Before the test, your doctor may ask you detailed questions about your symptoms. He/she may advise you to avoid certain medicines before the test, as they can interfere with the test results.

Let your doctor know if you have a family history of allergies.

Skin prick test: This test can identify if you are allergic to certain foods that may contain yeast. Here is how a skin prick test is done:

  • A laboratory technician will apply a small amount of the allergen on your skin.
  • He/she will use a needle (lancet) to prick the surface of the skin underneath the sample, so that the allergen can enter your skin.
  • The technician will then wait for some time to see if an itchy, red bump appears at the injection site, which will indicate that you have an allergy.

Blood test: This test is done to measure the number of IgE antibodies in blood. A laboratory technician will insert a sterile needle into a vein in your arm and withdraw a few millilitres of your blood. Once the sample is collected, the technician will label it with your name and date of collection and will send it for analysis.

After the procedure, you may notice mild bruising at the puncture site; it will fade in a few days. If you feel dizzy or lightheaded at the site of blood, please inform your doctor or nurse so that they can help you feel more comfortable.

A newer method has also been developed for testing yeast sensitivity, which involves the analysis of a stool sample.

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Normal results:

For the skin prick test: If the area of your skin around the sample application site does not show any changes, it means that you are not allergic to yeast.

For the blood test: The acceptable upper limit of IgE antibodies is between 150 and 300 international units per millilitre (UI)/mL, which suggests that you may not have an allergy.

Abnormal results:

For the skin prick test: A positive result indicates that you are allergic to yeast. A red, raised area at the injection site is interpreted as a positive result.

For the blood test: Higher than normal total IgE levels suggest that you may have an allergy. You may need to take an IgE test for a specific substance or food to identify whether you have an allergy to it.

If you are at risk of a strong allergic reaction, your doctor will provide you with an epinephrine device that you can use in case you experience a severe reaction.

Based on your symptoms and the test results, your doctor will devise a suitable treatment plan and also advise you about foods to avoid. If you have any questions about how to manage allergic complications, please speak with your doctor.

Disclaimer: All results must be clinically correlated with the patient’s complaints to make a complete and accurate diagnosis. The above information is provided from a purely educational point of view and is in no way a substitute for medical advice by a qualified doctor.

References

  1. Bansal RA, Tadros S, Bansal AS. Beer, Cider, and wine allergy. Case Reports Immunol. 2017;2017:7958924.
  2. American Academy of Allergy, Asthma and Immunology [Internet]. Milwaukee (WI). US; Immunoglobulin E (IgE) Definition
  3. American College of Allergy, Asthma and Immunology [internet]. Arlington Heights, Illinois, US; Food Allergy Testing
  4. Asthma and Allergy Foundation of America [Internet]. Landover (MD): Asthma and Allergy Foundation of America; Food Allergies
  5. Centers for Disease Control and Prevention [internet]. Atlanta (GA): US Department of Health and Human Services; Food Allergies
  6. Johns Hopkins Medicine [Internet]. The Johns Hopkins University, The Johns Hopkins Hospital, and Johns Hopkins Health System; Food Allergies
  7. Nemours Children’s Health System [Internet]. Jacksonville (FL): The Nemours Foundation; c2017; Allergy Testing
  8. National Heart, Lung, and Blood Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services; Blood Tests
  9. Kurowski Kurt. Food Allergies: Detection and Management. Am Fam Physician. 2008 Jun 15;77(12):1678-1686.
  10. University of Rochester Medical Center [Internet]. Rochester (NY): University of Rochester Medical Center; Diagnostic Tests for Allergies
  11. UW Health: American Family Children's Hospital [Internet]. Madison (WI): University of Wisconsin Hospitals and Clinics Authority; Allergy Tests
  12. Chiriac AM, Bousquet J, Demoly P. In vivo methods for the study and diagnosis of allergy. In: Adkinson NF Jr, Bochner BS, Burks AW, et al, eds. Middleton's Allergy: Principles and Practice. 8th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 70.
  13. Homburger HA, Hamilton RG. Allergic diseases. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 23rd ed. Philadelphia, PA: Elsevier; 2016:chap 55.
  14. Laurent J, Noirot C, Ansquer JC, Laurent G, Kestenbaum S, Lagrue G. Comment définir le taux normal des IgE sériques chez l'adulte? [How to define the normal level of serum IgE in adults?]. Ann Med Interne (Paris). 1985;136(5):419–422. PMID: 4062142.
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