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Sibofix is a commercial drug that is prescribed in the form of Tablet, Suspension. It is typically used for the treatment of Hepatic Encephalopathy. Other than this, Sibofix has some other therapeutic uses, which have been discussed ahead.
Medical history of the patient along with age and gender determines the dosage of Sibofix. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Detailed information has been provided in the dosage section.
Sibofix also has some side effects, the most common being Flatulence, Bloating or fullness, Constipation. Apart from the aforementioned side effects, Sibofix can also lead to other problems, which have been listed below. Usually, these side effects of Sibofix go away soon, and do not persist beyond the duration of the treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.
Sibofix's effect during pregnancy is Severe and Severe while nursing. Warnings related to Sibofix's effects on the liver, heart and kidney, if any, have been listed below.
Some other conditions that can be affected by Sibofix are listed in the contraindications section below.
Additionally, Sibofix may also adversely react with other medicines. See below for a complete list.
You should also be aware that Sibofix is safe while driving, and is addiction.
Sibofix is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| Adult |
|
| 13 - 18 years (Adolescent) |
|
| Geriatric |
|
Is the use of Sibofix safe for pregnant women?
Sibofix can cause severe side effects if taken during pregnancy, so, pregnant women should talk to their doctor before taking it.
Is the use of Sibofix safe during breastfeeding?
Sibofix should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.
What is the effect of Sibofix on the Kidneys?
Using Sibofix does not have any harmful effects on kidneys.
What is the effect of Sibofix on the Liver?
Sibofix may have mild side effects on the liver. Most people will never see any effect on the liver.
What is the effect of Sibofix on the Heart?
There are no any side effects of Sibofix for the heart.
Sibofix should not be taken with following medicines due to severe side effects it may cause to patients -
Moderate
If you are suffering from any of the following diseases, you should not take Sibofix unless your doctor advises you to do so -
Is this Sibofix habit forming or addictive?
No, you will not get addicted to Sibofix.
Is it safe to drive or operate heavy machinery when consuming?
Yes, it is safe to do these activities or work after taking Sibofix as it does not make you drowsy.
Is it safe?
Sibofix is safe but it is important to consult a doctor before taking it.
Is it able to treat mental disorders?
No, Sibofix is not used to treat mental disorders.
Interaction between Food and Sibofix
You can take Sibofix with food.
Interaction between Alcohol and Sibofix
It is difficult to say anything about the effect of Sibofix and alcohol. No research has been done on this yet.
Yes, Sibofix can be taken with amoxicillin. No clinically significant drug interaction has been reported between them. However, if you feel any discomfort after taking this drug along with amoxicillin then do not hesitate to inform your doctor.
No, Sibofix does not cause weight gain. It has not been reported by the patients who are taking this drug but Sibofix has been reported to cause weight loss in a few patients with travelers’ diarrhea. If you notice any unusual rapid weight changes after taking this drug then discuss with it your doctor and follow his/her instructions.
Sibofix is a brand name of rifaximin and it comes in the form of tablet and syrup. It is a prescription drug and a broad-spectrum antibiotic which is used in the prevention of travelers’ diarrhea (TD) caused by bacteria Escherichia coli and to reduce the risk of hepatic encephalopathy (a brain disorder that causes decline in functioning of the brain due to accumulation of ammonia in which results from the liver damage) along with lactulose. It is also used in the treatment of irritable bowel syndrome with diarrhea (IBS-D).
No, Sibofix is not a penicillin. It contains rifaximin which is a broad spectrum antibiotic and an analog of rifampicin. It is a prescription drug that is used in the treatment of travelers’ diarrhea (TD), hepatic encephalopathy, and irritable bowel syndrome with diarrhea (IBS-D).
Yes, Sibofix can be taken with loperamide. Loperamide does not appear to interfere with the efficacy of Sibofix. Hence, it is alright to take them together. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.
This medicine data has been created by -
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Xifaxan® (rifaximin)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 681-683
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1096-1097
