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Rifnim is a prescription medicine that is available as a Tablet. Hepatic Encephalopathy are some of its major therapeutic uses. The alternative uses of Rifnim have also been explained below.
The right dosage of Rifnim depends on the age, gender, and medical history of the patient. Individual symptoms and route of administration also determines the right dosage. Refer to the dosage section for a detailed discussion.
The side effects typically associated with Rifnim include Flatulence, Bloating or fullness, Constipation. While these are the most often observed Rifnim side effects, there are can be others also. These have been listed below. Usually, these side effects of Rifnim go away soon, and do not persist beyond the duration of the treatment. If, however, they worsen or do not go away, please speak with your physician.
Furthermore, you should know that effect of Rifnim is Severe for pregnant women and Severe for women who are breastfeeding. In addition, Rifnim's effects on the liver, heart and kidney are discussed below in the Rifnim related warnings section.
Some other conditions that can be affected by Rifnim are listed in the contraindications section below.
Besides this, Rifnim may also have severe interaction with some medicines. Refer to the list below for further details.
You should also be aware that Rifnim is safe while driving, and is addiction.
Rifnim is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| Adult |
|
| 13 - 18 years (Adolescent) |
|
| Geriatric |
|
Is the use of Rifnim safe for pregnant women?
Rifnim has many dangerous side effects in pregnant women. If you are pregnant, do not consume Rifnim without medical advice.
Is the use of Rifnim safe during breastfeeding?
Taking Rifnim may lead to serious side effects if you are breastfeeding. Rifnim should not be taken by breastfeeding women unless prescribed by the doctor.
What is the effect of Rifnim on the Kidneys?
Rifnim is not harmful for kidneys.
What is the effect of Rifnim on the Liver?
Side effects of Rifnim rarely affect the liver.
What is the effect of Rifnim on the Heart?
Rifnim is completely safe for the heart.
Rifnim should not be taken with following medicines due to severe side effects it may cause to patients -
Moderate
If you are suffering from any of the following diseases, you should not take Rifnim unless your doctor advises you to do so -
Is this Rifnim habit forming or addictive?
Rifnim is not addictive in nature.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can comfortably use machinery or drive after taking Rifnim since it will not make you feel sleepy.
Is it safe?
Yes, but consume Rifnim only on doctor's advice.
Is it able to treat mental disorders?
No, Rifnim cannot treat any kind of mental disorder.
Interaction between Food and Rifnim
It is safe to take Rifnim with food.
Interaction between Alcohol and Rifnim
No research has been done on this till date. Therefore, it is not known what the effect of taking Rifnim with alcohol will be.
Usually, Rifnim is given for short-term treatment 2 -14 days which might vary depending on the patient's medical condition. Take Rifnim as directed by your doctor to ensure complete eradication of infection. Do not take this medicine longer than prescribed duration to avoid bacterial resistance.
Yes, Rifnim can be taken with loperamide. Loperamide does not appear to interfere with the efficacy of Rifnim. Hence, it is alright to take them together. However, if you feel any discomfort after taking this drug do not hesitate to inform your doctor.
Yes, Rifnim is used in the treatment of irritable bowel syndrome with diarrhea (IBS-D). It has been found very effective for IBS-D. Rifnim is given three times a day up to 14 days in patients of irritable bowel syndrome with diarrhea.
Yes, Rifnim may cause orange urine because it is an analog of rifampicin. This side effect is reversible and unharmful in nature which goes away after discontinuation of this drug.
Rifnim works by inhibiting the bacterial protein synthesis which is essential for bacterial growth. The absence of these proteins results in stunned bacterial growth due to which bacteria is not able to survive. For hepatic encephalopathy Rifnim works by inhibiting the growth of enteric ammonia-producing bacteria which are present in our gut, this results in the indirect reduction of serum ammonia level. In irritable bowel syndrome with diarrhea, how Rifnim works are still unknown but it is presumed that it works by changing the bacterial flora in small intestine and reduction in gas.
This medicine data has been created by -
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Xifaxan® (rifaximin)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 681-683
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1096-1097
