Rifadox

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Rifadox Information

Rifadox is a commercial drug that is prescribed in the form of Tablet. Hepatic Encephalopathy are some of its major therapeutic uses. The alternative uses of Rifadox have also been explained below.

Medical history of the patient along with age and gender determines the dosage of Rifadox. Individual symptoms and route of administration also determines the right dosage. Refer to the dosage section for a detailed discussion.

The side effects typically associated with Rifadox include Flatulence, Bloating or fullness, Constipation. Besides the aforementioned side effects, there are other adverse effects of Rifadox as well, which are listed below. Usually, these side effects of Rifadox go away soon, and do not persist beyond the duration of the treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.

It is also important to note that Rifadox has a Severe effect for pregnant women and Severe effect on lactating mothers. Further, the section on Rifadox related warnings talks about Rifadox's effects on the liver, heart and kidney.

Other conditions have been mentioned below in the Rifadox contraindications section.

Drug interactions for Rifadox have been reported in the medical literature. Refer to the list below for further details.

Along with the above-mentioned precautions, remember that taking Rifadox is considered safe while driving, and is addictive.


Rifadox Benefits & Uses

Rifadox is used to treat the following -

Main Benefits

Other Benefits

Rifadox Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Traveler's Diarrhea
  • Before or After Meal: Either
  • Single Maximum Dose: 200 g
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Traveler's Diarrhea
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 2 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Traveler's Diarrhea
  • Before or After Meal: Either
  • Single Maximum Dose: 200 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: 3 days
  • Special Instructions: As prescribed by the doctor

Rifadox Related Warnings

  • Is the use of Rifadox safe for pregnant women?


    Rifadox should not be taken during pregnancy, or should only be taken on the advice of a doctor as it may have severe side effects.

    Severe
  • Is the use of Rifadox safe during breastfeeding?


    Rifadox should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Rifadox on the Kidneys?


    Rifadox does not damage the kidneys.

    Safe
  • What is the effect of Rifadox on the Liver?


    Rifadox is rarely harmful for the liver.

    Mild
  • What is the effect of Rifadox on the Heart?


    There are no any side effects of Rifadox for the heart.

    Safe

Severe Interaction of Rifadox with Other Drugs

Rifadox should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate


Rifadox Contraindications

If you are suffering from any of the following diseases, you should not take Rifadox unless your doctor advises you to do so -


Frequently asked Questions about Rifadox

  • Is this Rifadox habit forming or addictive?


    No, there is no any evidence that Rifadox is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, it is safe to do these activities or work after taking Rifadox as it does not make you drowsy.

    Safe
  • Is it safe?


    Rifadox is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Rifadox in mental disorders is not effective.

    No

Rifadox Interactions with Food and Alcohol

  • Interaction between Food and Rifadox


    Taking Rifadox with food does not cause any problems.

    Safe
  • Interaction between Alcohol and Rifadox


    No research has been done on this till date. Therefore, it is not known what the effect of taking Rifadox with alcohol will be.

    Unknown

Frequently asked Questions about Rifadox

Question over 5 years ago

Is Rifadox safe to use?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

Yes, Rifadox is safe to use, if taken in prescribed amount and duration as advised by the doctor. However, certain side effects have been associated with this drug such as dizziness, nausea, and vomiting. If you experience above-mentioned side effects after taking this drug then inform your doctor and follow his/her instructions.

Question almost 6 years ago

What is Rifadox?

Dr. Anand Singh MBBS , General Physician

Rifadox is a brand name of rifaximin and it comes in the form of tablet and syrup. It is a prescription drug and a broad-spectrum antibiotic which is used in the prevention of travelers’ diarrhea (TD) caused by bacteria Escherichia coli and to reduce the risk of hepatic encephalopathy (a brain disorder that causes decline in functioning of the brain due to accumulation of ammonia in which results from the liver damage) along with lactulose. It is also used in the treatment of irritable bowel syndrome with diarrhea (IBS-D). 

Question over 5 years ago

Can I discontinue Rifadox on my own without doctors advice?

Dr. Roshni Poonja MBBS , General Physician, Internal Medicine

Discontinuing Rifadox on your own can increase the chances of bacterial resistance and infection relapse. It is recommended that you always consult your doctor if you have decided to discontinue this medicine.

Question about 5 years ago

Is Rifadox helpful in treating irritable bowel syndrome (IBS)?

Dr. Chinmaya Bal MBBS , General Physician

Yes, Rifadox is used in the treatment of irritable bowel syndrome with diarrhea (IBS-D). It has been found very effective for IBS-D. Rifadox is given three times a day up to 14 days in patients of irritable bowel syndrome with diarrhea.

Question over 5 years ago

Can Rifadox cause bloating?

Dr. Ram Saini MD, MBBS , General Physician

No, Rifadox does not cause bloating. It has not been reported by the patients who are taking this drug. In fact Rifadox helps in reducing bloating and flatulence in irritable bowel syndrome (IBS) patients by controlling the bacterial overgrowth in the small intestine which is responsible for producing gas that causes bloating and flatulence.


See all substitutes for Rifadox


This medicine data has been created by -

Vikas Chauhan
B.Pharma, Pharmacy
5 Years of Experience

References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Xifaxan® (rifaximin)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 681-683

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 1096-1097

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