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Periset is a prescription drug, available for use as Injection, Syrup, Tablet. It is typically used for the treatment of Nausea and Vomiting.
The optimal dosage of Periset is largely dependent on the individual's body weight, medical history, gender and age. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. Refer to the dosage section for a detailed discussion.
Besides the aforementioned side effects, there are other adverse effects of Periset as well, which are listed below. Usually, these side effects of Periset go away soon, and do not persist beyond the duration of the treatment. Please speak with your doctor if these side effects worsen or persist for a longer duration.
It is also important to note that Periset has a Safe effect for pregnant women and Mild effect on lactating mothers. In addition, Periset's effects on the liver, heart and kidney are discussed below in the Periset related warnings section.
Periset is contraindicated in people with pre-existing medical conditions like Heart Disease, Calcium Deficiency, Potassium Deficiency as it can result in adverse effects. Other conditions have been mentioned below in the Periset contraindications section.
Additionally, Periset may also adversely react with other medicines. See below for a complete list.
In addition to these precautions, you may also note that Periset is not safe while driving, and is is not addictive in nature.
Periset is used to treat the following -
Main Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| Adult |
|
| Geriatric |
|
| 13 - 18 years (Adolescent) |
|
| 2 - 12 years (Child) |
|
| Infant (1 month to 2 years) |
|
Is the use of Periset safe for pregnant women?
Pregnant women can take Periset without worrying about any side effects.
Is the use of Periset safe during breastfeeding?
Side effects of Periset on breastfeeding women are very mild.
What is the effect of Periset on the Kidneys?
Using Periset does not have any harmful effects on kidneys.
What is the effect of Periset on the Liver?
There may be an adverse effect on the liver after taking Periset. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.
What is the effect of Periset on the Heart?
Periset may cause harmful effects on the heart. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.
Periset should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
If you are suffering from any of the following diseases, you should not take Periset unless your doctor advises you to do so -
Is this Periset habit forming or addictive?
No, there is no any evidence that Periset is addictive.
Is it safe to drive or operate heavy machinery when consuming?
After taking Periset, you should not drive or work on any heavy machine, as Periset can make you drowsy.
Is it safe?
Periset is safe but it is important to consult a doctor before taking it.
Is it able to treat mental disorders?
No, the use of Periset in mental disorders is not effective.
Interaction between Food and Periset
It is safe to take Periset with food.
Interaction between Alcohol and Periset
Consult your doctor before consuming alcohol while taking Periset as it can have severe side effects.
Yes, Periset is safe to be used in children from 6 months to 12 years of age. Apart from preventing nausea and vomiting related to chemotherapy and radiation, Periset can be used in this population group for managing acute gastritis. Acute gastritis presents itself as a self-limited infection with vomiting leading to dehydration and electrolyte imbalances. Always check with a child specialist and do not administer this drug yourself.
Periset is a brand name for ondansetron. It belongs to a class of compounds known as serotonin type 3 receptor antagonists. It is available in the form of tablet and injection. It is used to prevent nausea and vomiting that is caused by anti-cancer drugs, chemotherapy and radiation therapy. It is also used to prevent post-surgical nausea and vomiting.
Yes, Periset can be taken with pantoprazole as there are no records of any drug interaction. Pantoprazole is a proton pump inhibitor which is used for treating acidity. Acidity can be managed by avoiding eating acidic and spicy foods, avoiding smoking, and avoiding sleep within 3 hours of taking meals.
Periset is available in form of tablet, syrup, and injection. It should be taken as per your doctor's instructions. Ideally, Periset has to be taken with food to avoid stomach upset. The initial dose is usually taken half an hour before chemotherapy, 1 to 2 hours before radiation therapy and 1 hour before a surgery. Additional doses can be suggested by the doctor as per the individual requirements.
No, Periset should not be ideally taken with tramadol as the action of both the drugs decreases upon concomitant use. Tramadol is an opioid medication used to treat mild to moderate pain. Take it only when a doctor has prescribed it.
This medicine data has been created by -
References
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 947-948
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 668
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran (ondansetron hydrochloride)
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran® (ondansetron hydrochloride)
