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Orkacin is a commercial drug that is prescribed in the form of Injection. Primarily, it is used for the treatment of Urinary Tract Infection. Secondary and off-label uses of Orkacin have also been mentioned below.
The right dosage of Orkacin depends on the age, gender, and medical history of the patient. Dosage also depends on the route of administration and your chief complaint for which the drug is prescribed. This information has been provided in detail in the dosage section.
Besides the aforementioned side effects, there are other adverse effects of Orkacin as well, which are listed below. These side effects of Orkacin are usually temporary and subside with the completion of treatment. Consult your doctor if these side effects become worse or stay for a longer duration.
It is also important to note that Orkacin has a Severe effect for pregnant women and Unknown effect on lactating mothers. Further, the section on Orkacin related warnings talks about Orkacin's effects on the liver, heart and kidney.
Orkacin can cause adverse effects in certain medical conditions. It is strongly recommended to avoid Orkacin in conditions like Dehydration, Parkinson's Disease, Hearing Loss. Other conditions have been mentioned below in the Orkacin contraindications section.
Additionally, Orkacin may also adversely react with other medicines. See below for a complete list.
In addition to the above precautions for Orkacin, it is important to know that it is safe while driving, and is habit-forming.
Orkacin is used to treat the following -
Main Benefits
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
| Age Group | Dosage |
| Adult |
|
| Geriatric |
|
| 13 - 18 years (Adolescent) |
|
| Infant (1 month to 2 years) |
|
| Neonates (0 to 1 month) |
|
| 2 - 12 years (Child) |
|
Is the use of Orkacin safe for pregnant women?
Orkacin shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.
Is the use of Orkacin safe during breastfeeding?
Information about safety of Orkacin for women who are breastfeeding is not available since scientific research on this is yet to be done.
What is the effect of Orkacin on the Kidneys?
Effects of Orkacin on kidney can be severe. It is not safe to use it without doctor's advice.
What is the effect of Orkacin on the Liver?
Orkacin may have mild side effects on the liver. Most people will never see any effect on the liver.
What is the effect of Orkacin on the Heart?
Orkacin is rarely harmful for the heart.
Orkacin should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
If you are suffering from any of the following diseases, you should not take Orkacin unless your doctor advises you to do so -
Is this Orkacin habit forming or addictive?
No, there is no any evidence that Orkacin is addictive.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can operate a vehicle or heavy machinery after taking Orkacin since it does not cause drowsiness.
Is it safe?
Orkacin should be used only after doctor's advice.
Is it able to treat mental disorders?
Orkacin is unable to treat or cure mental disorders.
Interaction between Food and Orkacin
Taking Orkacin with food does not harm your health.
Interaction between Alcohol and Orkacin
It is difficult to say anything about the effect of Orkacin and alcohol. No research has been done on this yet.
No, Orkacin is not available in tablet form. It is available in only injectable dosage form either given by intramuscularly or intravenously depends on patient condition or severity of infections.
Yes, Orkacin has been reported to cause diarrhoea and it is a common side effect of this medicine. Drink plenty of fluids while you are taking this medicine. If you are experiencing severe diarrhoea after using this drug, discuss with your doctor immediately without any further delay.
Yes, Orkacin can be taken with lidocaine. The clinical report suggests that no harmful drug-drug interactions have been observed between them so far. However, it doesn't mean that no interaction could exist between them. These two medicines are high alert drug so you must consult your doctor before taking Orkacin together.
No, Orkacin cannot be taken with penicillin. Because penicillin inactivates the Orkacin by combining the beta-lactam ring of penicillin with an amino group of this drug to form amide which is biologically inactive. For this reason Orkacin should not be taken with penicillin. The chances of inactivation of this drug are higher in case of renal failure because in this case concentration of penicillin is higher in the kidney for a longer time as compared to the normal renal function.
No, Orkacin does not cause constipation in patients who are taking it. However, if you are experiencing constipation after taking this drug then inform your doctor and take precautionary methods such as eating fibrous foods to avoid constipation.
This medicine data has been created by -
References
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Arikayce (amikacin)
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 749
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 136-137
