Dr. Bharat MBBS , General Physician

The long-term use can lead to the deficiency of Vitamin B12, which can further lead to megaloblastic anemia. Furthermore, Long-term Metformin use can also lead to kidney and liver problems. 

ravi udawat MBBS , General Physician

Gledepa MET XR should be taken with food to reduce stomach and bowel side effects, which may experience the first few weeks of treatment. Also, exercise regularly and test for sugar in your blood or urine as directed.

Dr. Vedprakash Verma MBBS, MD , Cardiology

Yes, Gledepa MET XR is safe to use, many people have side effects at first, they usually diminish and then go away completely in a few weeks. A few people find they cannot tolerate metformin, there are other drugs but metformin is usually the first choice. It is very safe

Dr. Ayush Pandey MBBS, PG Diploma , General Physician

Yes, Gledepa MET XR can cause some sleep problems, especially insomnia. On the other hand, Gledepa MET XR has proven to be useful for preventing sleep apnea. The exact relationship between Gledepa MET XR and sleep problems is still not clear, and further studies are needed for a clearer understanding.

Dr. Ram Saini MD, MBBS , General Physician

Gledepa MET XR can be taken forever, diabetes is a progressive disease it's possible that more medication and/or insulin may eventually need to be added to the regime.